Ig G + Human Albumin Pharmacology

Ig G + Human Albumin

About Ig G + Human Albumin
N/A
Mechanism of Action of Ig G + Human Albumin
N/A
Pharmacokinets of Ig G + Human Albumin
N/A
Onset of Action for Ig G + Human Albumin
N/A
Duration of Action for Ig G + Human Albumin
N/A
Half Life of Ig G + Human Albumin
N/A
Side Effects of Ig G + Human Albumin
N/A
Contra-indications of Ig G + Human Albumin
N/A
Special Precautions while taking Ig G + Human Albumin
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Ig G + Human Albumin
N/A
Interactions for Ig G + Human Albumin
N/A
Typical Dosage for Ig G + Human Albumin
N/A
Schedule of Ig G + Human Albumin
N/A
Storage Requirements for Ig G + Human Albumin
N/A
Effects of Missed Dosage of Ig G + Human Albumin
N/A
Effects of Overdose of Ig G + Human Albumin
N/A

Ig G

About Ig G
Glycoprotein(Antibody), immune serum, Antibody production stimulator.
Mechanism of Action of Ig G
ImmunoglobulinG or IgG is the major class of immunoglobulins found in the blood. This is an extract of human (donor) blood which contains antibodies to diseases e.g. hepatitis A, measles, mumps, and German measles (rubella).
Pharmacokinets of Ig G
N/A
Onset of Action for Ig G
N/A
Duration of Action for Ig G
N/A
Half Life of Ig G
N/A
Side Effects of Ig G
. Rash
2. Fever (pyrexia)
3. Chills
4. Itching (pruritis)
5. Redness around injection site
6. Hardening of skin around injection site
7. Increased heart rate (tachycardia)
8. Malaise
9. Pain and swelling at site of injection
Contra-indications of Ig G
1. Hyper sensitivity to it
2. Vaccination with a live vaccine (e.g. oral polio, MMR) at the same time or in the previous 3 weeks
3. Immunoglobulin A (IgA) deficiency
4. Thrombocytopenia
5. Coagulation disorder
Special Precautions while taking Ig G
Use with caution in patients with a history of prior systemic allergic reactions following the administration of human immunoglobulin preparations.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Ig G
1. Preventing infection following burns injuries
2. Prevention of German measles following exposure in pregnancy
3. Prevention of Hepatitis A
4. Prevention of measles or reduction in measles symptoms following exposure in susceptible people 5. Reducing number and severity of infections in people with low levels of immunoglobulins in their blood
6. Agammaglobulinaemia/hypogammaglobulinaemia/dysgammaglobulinaemia
Interactions for Ig G
N/A
Typical Dosage for Ig G
Adults and children-
Intramuscular-
Hepatitis A:
Long term protection:0.06 mL/kg bodyweight
Short term protection: 0.03 mL/kg bodyweight
For prophylaxis long term, the injections should be given 5 monthly but serological checks should be made to assess if active immunity has developed.
The following doses of Normal Immunoglobulin are recommended for persons who plan
to travel in areas where hepatitis A is common
Length of stay <3 months- 0.03 mL/kg bodyweight
3 months or longer - 0.06 mL/kg bodyweight (repeat every 4-6 months)
Institutional contacts- 0.06 mL/kg bodyweight. Staff in institutions where hepatitis is endemic- A large dose (0.06 mL/kg bodyweight)
should be given at the time of employment, and this should be repeated at six-monthly
intervals if the risk persists.
Measles- 0.2 mL/kg bodyweight for prevention.
Poliomyelitis- 0.3 mL/kg bodyweight.
Hypogammaglobulinaemia- 0.6 mL/kg bodyweight at intervals of one month. An additional dose should be given during the first month of treatment
Schedule of Ig G
C
Storage Requirements for Ig G
Store at 2?C to 8?C (Refrigerate. Do not freeze). Protect from light
Effects of Missed Dosage of Ig G
N/A
Effects of Overdose of Ig G
Give supportive measures and symptomatic treatment

Human Albumin

About Human Albumin
Human plasma protein fraction, Transfusion material in Hypoalbuminemia.
Mechanism of Action of Human Albumin
Human albumin is an aqueous solution of frozen proteins obtained from plasma, serum, or placenta meant for intravenous administration.
Pharmacokinets of Human Albumin
N/A
Onset of Action for Human Albumin
N/A
Duration of Action for Human Albumin
N/A
Half Life of Human Albumin
N/A
Side Effects of Human Albumin
1. Allergic reactions
2. Salivation
3. Nausea
4. Vomiting
5. Fever
6. Chill
Contra-indications of Human Albumin
1. Hypersensitivity to Human albumin or blood products
2. Volume overload
3. Circulatory failure
4. Asystolia
Special Precautions while taking Human Albumin
1. In dehydration use with rehydrating fluids
2. Nephritis
3. In circulatory failure monitor central venous pressure
4. Renal impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Human Albumin
1. Plasma exchange
2. Hypovolaemic shock
3. Normovolaemic haemodilution burns
4. Neonatal jaundice
Interactions for Human Albumin
N/A
Typical Dosage for Human Albumin
I.V.:
Shock:
Adults: 100 to 200ml.
Children: 1 to 2ml/kg body weight.
Burns: Initially 200 to 400ml; on 1st day followed by 100 to 200ml. or 2 to 4ml/kg body weight.
Neonatal jaundice: 10 to 15ml with exchange transfusion. Do not exceed 20 drops/minute.
Schedule of Human Albumin
C
Storage Requirements for Human Albumin
Store at a temperature range of 2 to 8 degree C.
Effects of Missed Dosage of Human Albumin
The doctor should be informed immediately if a dose is missed.
Effects of Overdose of Human Albumin
Give supportive measures and symptomatic treatment.

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