Cefaloridine Pharmacology


About Cefaloridine
A first-generation cephalosporin antibiotic.
Mechanism of Action of Cefaloridine
Cephaloridine is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephaloridine inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephaloridine
Pharmacokinets of Cefaloridine
Absorption: Orally not well absorbed & should be given parenterally, Distribution: widely distributed, Metabolism: Not metabolized, Excretion: Excreted mainly through urine & small amount is seen in breast milk.
Onset of Action for Cefaloridine
Half an hour
Duration of Action for Cefaloridine
6 hours
Half Life of Cefaloridine
Side Effects of Cefaloridine
1.Pain after I.M. injection & thrombophlebitis after I.V. injection.
2.Rashes & allergic manifestation
7.Pseudo membranous colitis
Contra-indications of Cefaloridine
1.Hypersensitivity to cephalosporins
2.Along with other nephrotoxic drugs
3.Along with oral anticoagulants
4.Pseudo membranous colitis
Special Precautions while taking Cefaloridine
1.Renal impairment
2.Those allergic to penicillins
3. Neuromuscular disorders
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Cefaloridine
1.Respiratory tract infections
3.Skin & Soft tissue infections
4.Urinary tract & genital tract infections
5.Surgical prophylaxis
6.Bone & Joint infections
Interactions for Cefaloridine
Aminoglycosides: Enhance half-life and potentiate nephrotoxicity.
Probenecid: Prolongs activity by slowing tubular excretion.
Typical Dosage for Cefaloridine
Adults: 1gm to1.5gm daily in two or three divided doses I.M. or I.V.
In severe infections: 1.5 gm 8 hourly or 12 hourly.
Children: 15 to 30 mg/kg/day in divided doses
In severe infections: 40 to 100mg/kg/day
Maximum adult dose: Up to 6gm/day
Maximum child dose: Up to 4gm/day
Schedule of Cefaloridine
Storage Requirements for Cefaloridine
Store in a refrigerator.
Effects of Missed Dosage of Cefaloridine
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Cefaloridine
Symptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measures

Home Delivery for Cefaloridine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cefaloridine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cefaloridine and other medicines and health products. Home delivery services for cefaloridine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cefaloridine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cefaloridine before they complete the sale. You can get this information while placing the order for cefaloridine with the pharmacy.

Cefaloridine is a generic medicine name and there are several brands available for it. Some of the brands for cefaloridine might be better known than cefaloridine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefaloridine in stock, you can ask for one of the branded alternatives for cefaloridine.