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- Pharmacology For Spirulina + Mecobalamin + Vit B5 + Calcium
Spirulina + Mecobalamin + Vit B5 + Calcium Pharmacology
Spirulina + Mecobalamin + Vit B5 + Calcium
About Spirulina + Mecobalamin + Vit B5 + CalciumN/AMechanism of Action of Spirulina + Mecobalamin + Vit B5 + CalciumN/APharmacokinets of Spirulina + Mecobalamin + Vit B5 + CalciumN/AOnset of Action for Spirulina + Mecobalamin + Vit B5 + CalciumN/ADuration of Action for Spirulina + Mecobalamin + Vit B5 + CalciumN/AHalf Life of Spirulina + Mecobalamin + Vit B5 + CalciumN/ASide Effects of Spirulina + Mecobalamin + Vit B5 + CalciumN/AContra-indications of Spirulina + Mecobalamin + Vit B5 + CalciumN/ASpecial Precautions while taking Spirulina + Mecobalamin + Vit B5 + CalciumN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Spirulina + Mecobalamin + Vit B5 + CalciumN/AInteractions for Spirulina + Mecobalamin + Vit B5 + CalciumN/ATypical Dosage for Spirulina + Mecobalamin + Vit B5 + CalciumN/ASchedule of Spirulina + Mecobalamin + Vit B5 + CalciumN/AStorage Requirements for Spirulina + Mecobalamin + Vit B5 + CalciumN/AEffects of Missed Dosage of Spirulina + Mecobalamin + Vit B5 + CalciumN/AEffects of Overdose of Spirulina + Mecobalamin + Vit B5 + CalciumN/ASpirulina
About SpirulinaEdible blue-green algae, Dietary supplement.Mechanism of Action of SpirulinaSpirulina exerts its action by being a richest food supplements. It is a good source of proteins (60 to 70%) and also contains vitamins, minerals, carbohydrates, lipids, fibres, organic nitrogen, antioxidants, phycocyanobilin etc. The protein content of Spirulina is 85 to 95% digestible. Fat content (5 to 7%) of Spirulina is in the form of essential fatty acids in the form of linolenic acid and gamma linolenic acid.
Gamma linolenic acid elevates HDL levels and improves fatty acid profile and act as a precursor of PGE1 which prevents platelet aggregation in blood vessels and also controls inflammations. It is a richest source of anti oxidants like superoxide dumatase enzyme and beta-carotene. It also contains high concentrations of B complex vitamins. Phycocyanobilin which is a linear tetrapyrrole related to haem forms Phycocyanin which forms soluble complexes with iron and other minerals and is in an easily absorbable form.
Pharmacokinets of SpirulinaN/AOnset of Action for SpirulinaN/ADuration of Action for SpirulinaN/AHalf Life of SpirulinaN/ASide Effects of SpirulinaNo known adverse effectsContra-indications of SpirulinaNo known contraindicationsSpecial Precautions while taking SpirulinaN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Spirulina1.Nutritional supplement
2.Antioxidant for preventing diseases caused by free radicals
3.Stimulant for thyroid gland
4.Stimulation of immune system and prostaglandin levels
5.Probiotic for building body`s resistance
6.Prevention of atherosclerosis
7.Prevention of platelet aggregation and dilation of blood vessels
8.Prevention of xerophthalmia, cataract, and night blindness
9.Therapeutic supplement in treatment of malignancy, pancreatitis, cirrhosis, hepatitis
10.Prophylaxis against precancerous lesions like oral leukoplakia and submucous fibrosis
11.Controle of diabetes
12.Dietary supplement in adults, sportsmen, growing and malnourished childrenInteractions for SpirulinaN/ATypical Dosage for SpirulinaOral: 1000mg 12th hourly for 2months; then 500mg 12th hourly for the following two months.Schedule of SpirulinaN/AStorage Requirements for SpirulinaN/AEffects of Missed Dosage of SpirulinaN/AEffects of Overdose of SpirulinaN/AMecobalamin
About MecobalaminWater soluble, Form of Vitamin B12Mechanism of Action of MecobalaminMecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.Pharmacokinets of MecobalaminAbsorption: Absorbed after oral, sublingual, injection
Excretion: Excretion via urine
Onset of Action for MecobalaminN/ADuration of Action for MecobalaminN/AHalf Life of MecobalaminN/ASide Effects of Mecobalamin1.Oral: Anorexia, nausea, vomiting and diarrhea
2.Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site
Contra-indications of MecobalaminN/ASpecial Precautions while taking MecobalaminN/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Mecobalamin1.Peripheral neuropathies
2.Megaloblastic anaemia
Interactions for Mecobalamin1.Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicines
2.Reduced serum concentrations with oral contraceptives
3.Reduced effects in anaemia with parenteral chloramphenicol
Typical Dosage for MecobalaminPeripheral neuropathies
Oral: Adult: 1500 mcg/day in 3 divided doses
Parenteral: 500 mcg daily IM/IV 3 times/wk
Megaloblastic anaemia caused by vitamin B12 deficiency
Parenteral: Adult: 500 mcg daily IM/IV 3 times/wk. Maintenance dose: After about 2 mth of therapy, reduce dose to single admin of 500 mcg every 1-3 mth.Schedule of MecobalaminN/AStorage Requirements for MecobalaminOral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Effects of Missed Dosage of MecobalaminN/AEffects of Overdose of MecobalaminN/AVit B5
About Vit B5Vitamin , A water-soluble B complex vitamin.Mechanism of Action of Vit B5Pantothenic acid exerts it`s actions by influencing metabolic reactions. It is a component of coenzyme-A which functions in carbohydrate, fat, steroid and porphyrin metabolism by catalyzing acetate transfer reactions.
Pharmacokinets of Vit B5Absorption: Well absorbed orally.
Distribution: Widely distributed in the body tissues, and appears in the breast milk.
Excretion: 70% excreted unchanged in urine and 30% in faeces.
Onset of Action for Vit B5N/ADuration of Action for Vit B5N/AHalf Life of Vit B5N/ASide Effects of Vit B5N/AContra-indications of Vit B5N/ASpecial Precautions while taking Vit B5N/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Vit B51. Nutritional supplement in conjunction with other B vitamins
2. Post operative paralytic ileus.
Interactions for Vit B5Tetracycline: Vitamin B5 should not be taken at the same time as the Tetracycline because it interferes with the absorption and effectiveness of this medication.
B vitamins should be taken at different times from tetracycline.
Typical Dosage for Vit B5Oral: 50 to 100mg daily.Schedule of Vit B5C1Storage Requirements for Vit B5Store in a well closed container; in a cool place and protect from light.Effects of Missed Dosage of Vit B5Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vit B5Provide symptomatic treatment and supportive measures.Calcium
About CalciumCalcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.Mechanism of Action of CalciumCalcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.
Pharmacokinets of CalciumAbsorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.Onset of Action for CalciumN/ADuration of Action for CalciumN/AHalf Life of CalciumN/ASide Effects of Calcium1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion
Contra-indications of Calcium1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.
Special Precautions while taking Calcium1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Calcium1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.
Interactions for CalciumN/ATypical Dosage for CalciumOral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.
Schedule of CalciumN/AStorage Requirements for CalciumStore in a well closed container in a cool and dry place. Protect from light.
Effects of Missed Dosage of CalciumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CalciumRemove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.Home Delivery for Spirulina + Mecobalamin + Vit B5 + Calcium in Your City
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