Cefadroxil Pharmacology


About Cefadroxil
First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic
Mechanism of Action of Cefadroxil
Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil

Pharmacokinets of Cefadroxil
Absorption: well absorbed orally, Distribution: widely distributed, Metabolism: not metabolized, Excretion: excreted mainly through urine; & small amount is excreted in breast milk.
Onset of Action for Cefadroxil
Within one hour
Duration of Action for Cefadroxil
Up to16 hours
Half Life of Cefadroxil
Side Effects of Cefadroxil
5.Super infection
8.Hypersensitivity reactions
17.Elevated liver enzymes.
Contra-indications of Cefadroxil
1.Hypersensitivity to cephalosporins
3.Neuromuscular disorders.
Special Precautions while taking Cefadroxil
1.Renal impairment
2.Patient allergic to penicillins
3.Neuromuscular disorders
Pregnancy Related Information
Use with caution.
Old Age Related Information
May be used.
Breast Feeding Related Information
Use with caution.
Children Related Information
May be used.
Indications for Cefadroxil
1. Urinay tract infections
2. Tonsillitis & Pharyngitis
3. Skin &soft tissue infections
4. Otitis media.
Interactions for Cefadroxil
Aminoglycosides (Gentamycin, Tobramycin): Nephrotoxicity of aminoglycosides potentiated.
Oral anticoagulants: Hypoprothrombinaemic effect potentiated, bleeding complications may occur.
Bacteriostatic Agents like Chloramphenicol: Decrease efficacy of Cefadroxil.
Probenecid: Slows tubular excretion and this enhances efficacy.
Frusemide & Ethacrynic Acid: Potentiate Nephrotoxicity of Cefadroxil.
Urine Glucose: False positive with Benedicts solution and Fehlings solution.
Direct Coomb?s Test: False positive.
Urinary 17-Ketosteroid values: Falsely elevated values.

Typical Dosage for Cefadroxil
Adults:500mg to 1gm 12 hourly
Children:30mg/kg/day two times daily
Schedule of Cefadroxil
Storage Requirements for Cefadroxil
Store in a cool place.

Effects of Missed Dosage of Cefadroxil
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Cefadroxil
Symptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measures

Home Delivery for Cefadroxil in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cefadroxil.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cefadroxil and other medicines and health products. Home delivery services for cefadroxil may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cefadroxil only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cefadroxil before they complete the sale. You can get this information while placing the order for cefadroxil with the pharmacy.

Cefadroxil is a generic medicine name and there are several brands available for it. Some of the brands for cefadroxil might be better known than cefadroxil itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefadroxil in stock, you can ask for one of the branded alternatives for cefadroxil.