Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract Pharmacology

Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract

About Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Mechanism of Action of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Pharmacokinets of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Onset of Action for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Duration of Action for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Half Life of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Side Effects of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Contra-indications of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Special Precautions while taking Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Interactions for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Typical Dosage for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Schedule of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Storage Requirements for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Effects of Missed Dosage of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Effects of Overdose of Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract
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Vitamin E

About Vitamin E
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Mechanism of Action of Vitamin E
Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.
Pharmacokinets of Vitamin E
Absorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin E
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Duration of Action for Vitamin E
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Half Life of Vitamin E
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Side Effects of Vitamin E
1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence


Contra-indications of Vitamin E
1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E
1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related Information
May be used
Old Age Related Information
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Breast Feeding Related Information
May be used
Children Related Information
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Indications for Vitamin E
1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant


Interactions for Vitamin E
Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.

Typical Dosage for Vitamin E
Oral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.



Schedule of Vitamin E
C1
Storage Requirements for Vitamin E
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Vitamin E
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin E
Provide supportive measures and symptomatic treatment.

Lutein

About Lutein
Carotenoid, Xanthophyll, Dietary antioxidant.
Mechanism of Action of Lutein
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Pharmacokinets of Lutein
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Onset of Action for Lutein
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Duration of Action for Lutein
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Half Life of Lutein
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Side Effects of Lutein
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Contra-indications of Lutein
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Special Precautions while taking Lutein
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Lutein
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Interactions for Lutein
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Typical Dosage for Lutein
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Schedule of Lutein
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Storage Requirements for Lutein
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Effects of Missed Dosage of Lutein
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Effects of Overdose of Lutein
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Beta Carotene

About Beta Carotene
A natural precursor to Vitamin A.
Mechanism of Action of Beta Carotene
Beta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.
Pharmacokinets of Beta Carotene
Absorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta Carotene
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Duration of Action for Beta Carotene
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Half Life of Beta Carotene
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Side Effects of Beta Carotene
Adverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene
1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene
1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Beta Carotene
1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta Carotene
Cholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.
Typical Dosage for Beta Carotene
Severe vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta Carotene
C1 (Oral)
C (Parenteral)
Storage Requirements for Beta Carotene
Store in a well closed, airtight container in a cool dry place.
Effects of Missed Dosage of Beta Carotene
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Beta Carotene
Discontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage.

Lycopene

About Lycopene
Carotenoid;Terpenes and terpenoids, Dietary antioxidant.
Mechanism of Action of Lycopene
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Pharmacokinets of Lycopene
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Onset of Action for Lycopene
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Duration of Action for Lycopene
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Half Life of Lycopene
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Side Effects of Lycopene
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Contra-indications of Lycopene
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Special Precautions while taking Lycopene
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Lycopene
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Interactions for Lycopene
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Typical Dosage for Lycopene
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Schedule of Lycopene
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Storage Requirements for Lycopene
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Effects of Missed Dosage of Lycopene
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Effects of Overdose of Lycopene
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Minerals

About Minerals
Dietary mineral supplement, Nutritional supplement.
Mechanism of Action of Minerals
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Pharmacokinets of Minerals
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Onset of Action for Minerals
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Duration of Action for Minerals
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Half Life of Minerals
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Side Effects of Minerals
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Contra-indications of Minerals
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Special Precautions while taking Minerals
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Minerals
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Interactions for Minerals
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Typical Dosage for Minerals
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Schedule of Minerals
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Storage Requirements for Minerals
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Effects of Missed Dosage of Minerals
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Effects of Overdose of Minerals
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Grape Seed Extract

About Grape Seed Extract
Vitamin E, flavonoids, linoleic acid, and OPCs are highly concentrated in grape seeds.
Mechanism of Action of Grape Seed Extract
It is rich in flavonoids, which are plant substances that help protect cells from free radical damage. Grape Seed Extract is a natural plant substance that has a concentrated source of oligomeric proanthocyanidins (OPC). These anti-oxidants help protect cells from free radical damage and also promote healthy circulation. Grape Seed Extract is rich in polyphenols, a compound that's high in antioxidants. Studies have shown OPC to be more powerful antioxidants than vitamin C, E, and beta-carotene. Grape Seed Extract is both water and fat-soluble and may therefore penetrate all types of cell membranes delivering powerful antioxidant protection. It is also one of the few antioxidants that can cross the blood brain barrier, potentially helping to protect brain cells from free radical damage.
Pharmacokinets of Grape Seed Extract
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Onset of Action for Grape Seed Extract
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Duration of Action for Grape Seed Extract
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Half Life of Grape Seed Extract
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Side Effects of Grape Seed Extract
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Contra-indications of Grape Seed Extract
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Special Precautions while taking Grape Seed Extract
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Grape Seed Extract
1.Reduction of blood cholesterol
2.Cardiovascular diseases
3.Generalized well being
Interactions for Grape Seed Extract
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Typical Dosage for Grape Seed Extract
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Schedule of Grape Seed Extract
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Storage Requirements for Grape Seed Extract
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Effects of Missed Dosage of Grape Seed Extract
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Effects of Overdose of Grape Seed Extract
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Home Delivery for Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract and other medicines and health products. Home delivery services for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract before they complete the sale. You can get this information while placing the order for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract with the pharmacy.

Vitamin E + Lutein + Beta Carotene + Lycopene + Minerals + Grape Seed Extract is a generic medicine name and there are several brands available for it. Some of the brands for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract might be better known than vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract itself. If the pharmacy that's willing to deliver medicines to your home doesn't have vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract in stock, you can ask for one of the branded alternatives for vitamin e + lutein + beta carotene + lycopene + minerals + grape seed extract.