Epoetin Beta Pharmacology

Epoetin Beta

About Epoetin Beta
Synthetic recombinant form of erythropoietin, erythropoiesis stimulant,antianaemic.
Mechanism of Action of Epoetin Beta
Erythropoietin regulates erythropoiesis by stimulating the differentiation and proliferation of erythroid precursors, stimulating the release of reticulocytes into the circulation, and synthesis of cellular haemoglobin.
Pharmacokinets of Epoetin Beta
Onset of Action for Epoetin Beta
Duration of Action for Epoetin Beta
Half Life of Epoetin Beta
Side Effects of Epoetin Beta
4.Flu-like syndrome
5.Rashes and urticaria
6.Dangerous: Hypertensive crisis with encephalopathy-like symptoms e.g. Headache, confusion, generalised seizures,Thrombosis.
Contra-indications of Epoetin Beta
1.Uncontrolled hypertension
2.Hypersensitivity to mammalian cell products and human albumin
3.Special Precautions:
4.Chronic renal failure
5.Ischaemic heart diseases
8.Liver dysfunction
Special Precautions while taking Epoetin Beta
Pregnancy Related Information
Use with caution
Old Age Related Information
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Epoetin Beta
1.Anaemia of chronic renal failure
2.Anaemia related to non-myeloid malignant disease chemotherapy
3.Anaemia of prematurity
4.Increase yield of autologous blood
Interactions for Epoetin Beta
1.Haematinics enhance efficiency
2.Increased dose of heparin in patients undergoing dialysis
Typical Dosage for Epoetin Beta
1.Anaemia of chronic renal failure
Adult: Given via SC route: 60 units/kg/wk for 4 wk. Dose may be divided to be given on daily or 3 times/wk. When admin via IV, initial dose: 40 units/kg 3 times/wk for 4 wk. May be increased to 80 units/kg 3 times/wk. For SC and IV routes, subsequent doses can be increased at 60 units/kg/wk until target is reached. Max Dosage: 720 units/kg/wk
2.Anaemia related to non-myeloid malignant disease chemotherapy
Adult: Subcutaneous ;450 units/kg/wk. May be divided into 3-7 doses for solid tumours, multiple myeloma, low-grade Hodgkin's disease, chronic lymphocytic leukaemia. May double dose after 4 wk, if necessary. Treatment may continue for up to a mth after chemotherapy. If no adequate response is achieved after 4 wk at higher dose, then treatment should be stopped
3.Anaemia of prematurity
Adult: Subcutaneous :250 units/kg 3 times wkly. Treatment should be started as early as possible and continued for 6 wk
4.Increase yield of autologous blood
Adult: Parenteral :Up to 800 units/kg IV, or up to 600 units/kg SC, twice wkly for 4 wk before surgery
Schedule of Epoetin Beta
Storage Requirements for Epoetin Beta
Intravenous: Refrigerate at 2-8?C. Do not freeze
Parenteral: Refrigerate at 2-8?C. Do not freeze
Subcutaneous: Refrigerate at 2-8?C. Do not freeze
Effects of Missed Dosage of Epoetin Beta
Effects of Overdose of Epoetin Beta

Home Delivery for Epoetin Beta in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for epoetin beta and other medicines and health products. Home delivery services for epoetin beta may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take epoetin beta only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for epoetin beta before they complete the sale. You can get this information while placing the order for epoetin beta with the pharmacy.

Epoetin Beta is a generic medicine name and there are several brands available for it. Some of the brands for epoetin beta might be better known than epoetin beta itself. If the pharmacy that's willing to deliver medicines to your home doesn't have epoetin beta in stock, you can ask for one of the branded alternatives for epoetin beta.