Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6 Pharmacology

Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6

About Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Mechanism of Action of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Pharmacokinets of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Onset of Action for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Duration of Action for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Half Life of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Side Effects of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Contra-indications of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Special Precautions while taking Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
Use with caution
Children Related Information
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Indications for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
1.Cardiovascular diseases
2.Nutritional supplement
3.Antioxidant
Interactions for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Typical Dosage for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Schedule of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Storage Requirements for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Effects of Missed Dosage of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Effects of Overdose of Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6
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Omega 3 Fatty acids

About Omega 3 Fatty acids
They are polyunsaturated fatty acids with a double bond (C=C) starting after the third carbon atom from the end of the carbon chain.
Mechanism of Action of Omega 3 Fatty acids
Omega-3 polyunsaturated fatty acids work by lowering the body's production of triglycerides. High levels of triglycerides can lead to coronary artery disease, heart disease, and stroke.Omega-3 polyunsaturated fatty acids are used together with diet and exercise to help lower triglyceride levels in the blood.
They include eicosapentaenoic acid ,docosahexaenoic acid and ?-linolenic acid
Pharmacokinets of Omega 3 Fatty acids
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Onset of Action for Omega 3 Fatty acids
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Duration of Action for Omega 3 Fatty acids
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Half Life of Omega 3 Fatty acids
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Side Effects of Omega 3 Fatty acids
1.Back pain
2.Unusual or unpleasant taste in your mouth
3.Upset stomach, belching
4.Mild skin rash
Contra-indications of Omega 3 Fatty acids
Hypersensitivity to drug or fish or soybeans.
Special Precautions while taking Omega 3 Fatty acids
1.Diabetes
2.Liver disease
3.Pancreas disorder
4.Underactive thyroid
5.If drink more than 2 alcoholic beverages per day
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Not recommended
Indications for Omega 3 Fatty acids
1.Pre-existing coronary heart disease
2.Atherosclerosis related disorders e.g. Hyperlipidaemia
3.Diabetes
4.Obesity
5.Hypertension
6.Lipid rich diet
Interactions for Omega 3 Fatty acids
1.Estrogens (birth control pills or hormone replacement)
2.Blood thinner such as warfarin can increase risk of bleeding
3.Beta-blockers
4.Diuretics
Typical Dosage for Omega 3 Fatty acids
Usual Adult Dose for Hypertriglyceridemia:

Omega-3 polyunsaturated fatty acids - Nutritional Supplement
General dosage range 1 to 2 capsules 3 times a day with meals

Omega-3-acid ethyl esters
Dosage: 4 grams per day as either a single 4 gram dose or as a 2 gram dose twice a day
Schedule of Omega 3 Fatty acids
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Storage Requirements for Omega 3 Fatty acids
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Effects of Missed Dosage of Omega 3 Fatty acids
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Effects of Overdose of Omega 3 Fatty acids
Seek emergency medical attention.

Vitamin C

About Vitamin C
Water soluble vitamin, antioxidant.
Mechanism of Action of Vitamin C
Vitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.
Pharmacokinets of Vitamin C
Absorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin C
N/A
Duration of Action for Vitamin C
N/A
Half Life of Vitamin C
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Side Effects of Vitamin C
1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria
Contra-indications of Vitamin C
No known contraindications
Special Precautions while taking Vitamin C
1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Vitamin C
1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries

Interactions for Vitamin C
Oral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.
Typical Dosage for Vitamin C
Oral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.

Schedule of Vitamin C
C1 (Oral)
C (Parenteral)
Storage Requirements for Vitamin C
Store in a cool dry area in a well closed container. Protects from moisture, light and direct heat.
Effects of Missed Dosage of Vitamin C
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin C
Discontinue the therapy and provide symptomatic and supportive measures.

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Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
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Side Effects of Folic Acid
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Contra-indications of Folic Acid
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Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Zinc

About Zinc
Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.
Mechanism of Action of Zinc
Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.
Pharmacokinets of Zinc
Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.
Onset of Action for Zinc
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Duration of Action for Zinc
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Half Life of Zinc
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Side Effects of Zinc
1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of Zinc
N/A
Special Precautions while taking Zinc
1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc
1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for Zinc
Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc
Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of Zinc
N/A
Storage Requirements for Zinc
Store at a temperature below 30 degree C
Effects of Missed Dosage of Zinc
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Zinc
Provide symptomatic treatment and supportive measures

Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
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Pharmacokinets of Selenium
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Onset of Action for Selenium
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Duration of Action for Selenium
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Half Life of Selenium
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Side Effects of Selenium
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Contra-indications of Selenium
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Special Precautions while taking Selenium
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Selenium
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Interactions for Selenium
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Typical Dosage for Selenium
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Schedule of Selenium
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Storage Requirements for Selenium
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Effects of Missed Dosage of Selenium
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Effects of Overdose of Selenium
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Mecobalamin

About Mecobalamin
Water soluble, Form of Vitamin B12
Mechanism of Action of Mecobalamin
Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Pharmacokinets of Mecobalamin
Absorption: Absorbed after oral, sublingual, injection
Excretion: Excretion via urine
Onset of Action for Mecobalamin
N/A
Duration of Action for Mecobalamin
N/A
Half Life of Mecobalamin
N/A
Side Effects of Mecobalamin
1.Oral: Anorexia, nausea, vomiting and diarrhea
2.Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site
Contra-indications of Mecobalamin
N/A
Special Precautions while taking Mecobalamin
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
N/A
Indications for Mecobalamin
1.Peripheral neuropathies
2.Megaloblastic anaemia
Interactions for Mecobalamin
1.Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicines
2.Reduced serum concentrations with oral contraceptives
3.Reduced effects in anaemia with parenteral chloramphenicol
Typical Dosage for Mecobalamin
Peripheral neuropathies
Oral: Adult: 1500 mcg/day in 3 divided doses
Parenteral: 500 mcg daily IM/IV 3 times/wk

Megaloblastic anaemia caused by vitamin B12 deficiency
Parenteral: Adult: 500 mcg daily IM/IV 3 times/wk. Maintenance dose: After about 2 mth of therapy, reduce dose to single admin of 500 mcg every 1-3 mth.
Schedule of Mecobalamin
N/A
Storage Requirements for Mecobalamin
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.


Effects of Missed Dosage of Mecobalamin
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Effects of Overdose of Mecobalamin
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Vit B6

About Vit B6
Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.
Mechanism of Action of Vit B6
Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.
Pharmacokinets of Vit B6
Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver
Onset of Action for Vit B6
N/A
Duration of Action for Vit B6
N/A
Half Life of Vit B6
15-20 days
Side Effects of Vit B6
1. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia
Contra-indications of Vit B6
1. Hypersensitivity to Vitamin B6
Special Precautions while taking Vit B6
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Vit B6
1. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning
Interactions for Vit B6
Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.
Typical Dosage for Vit B6
Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.
Schedule of Vit B6
N/A
Storage Requirements for Vit B6
Store it at 15 - 30 degree C. Protect from moisture and heat.
Effects of Missed Dosage of Vit B6
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B6
Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.

Home Delivery for Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6 in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6 and other medicines and health products. Home delivery services for omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Omega 3 Fatty Acids + Vitamin C + Vitamin E + Folic Acid + Zinc + Selenium + Mecobalamin + Vit B6 is a generic medicine name and there are several brands available for it. Some of the brands for omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6 might be better known than omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6 in stock, you can ask for one of the branded alternatives for omega 3 fatty acids + vitamin c + vitamin e + folic acid + zinc + selenium + mecobalamin + vit b6.