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- Pharmacology For Chlorpheniramine Maleate + Sodium Citrate + Paracetamol
Chlorpheniramine Maleate + Sodium Citrate + Paracetamol Pharmacology
Chlorpheniramine Maleate + Sodium Citrate + Paracetamol
About Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AMechanism of Action of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/APharmacokinets of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AOnset of Action for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/ADuration of Action for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AHalf Life of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/ASide Effects of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AContra-indications of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/ASpecial Precautions while taking Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolCough and coldInteractions for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/ATypical Dosage for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/ASchedule of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AStorage Requirements for Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AEffects of Missed Dosage of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AEffects of Overdose of Chlorpheniramine Maleate + Sodium Citrate + ParacetamolN/AChlorpheniramine Maleate
About Chlorpheniramine MaleateN/AMechanism of Action of Chlorpheniramine MaleateN/APharmacokinets of Chlorpheniramine MaleateN/AOnset of Action for Chlorpheniramine MaleateN/ADuration of Action for Chlorpheniramine MaleateN/AHalf Life of Chlorpheniramine MaleateN/ASide Effects of Chlorpheniramine MaleateN/AContra-indications of Chlorpheniramine MaleateFirst Generation alkylamine H1 Antagonist, Antihistamine.Special Precautions while taking Chlorpheniramine MaleateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Chlorpheniramine MaleateN/AInteractions for Chlorpheniramine MaleateN/ATypical Dosage for Chlorpheniramine MaleateN/ASchedule of Chlorpheniramine MaleateN/AStorage Requirements for Chlorpheniramine MaleateN/AEffects of Missed Dosage of Chlorpheniramine MaleateN/AEffects of Overdose of Chlorpheniramine MaleateN/ASodium citrate
About Sodium citrateSodium compound,citrates, Urinary alkalinizing agent, a directly acing expectorant.Mechanism of Action of Sodium citrateSodium citrate is an alkalinizing agent which is used to make the urine more alkaline (less acidic).It prevents certain kinds of kidney stones and also relieve discomfort in mild urinary tract infections such as cystitis. Sodium citrate also makes the blood more alkaline in certain conditions. Sodium citrate is a directly acing expectorant which increases bronchial secretion by salt action.Pharmacokinets of Sodium citrateAbsorption: Administered orally, Metabolism: Metabolized in to sodium bicarbonate, Excretion: Excreted through urine.Onset of Action for Sodium citrateN/ADuration of Action for Sodium citrateN/AHalf Life of Sodium citrateN/ASide Effects of Sodium citrate1. Polyuria
2. Hypernatremia
3. Metabolic alkalosis
4. Diarrhea
5. Loose bowel movements
6. Allergic reactions (rare)
7. Chest pain (rare)
8. Shortness of breath (rare)
Contra-indications of Sodium citrateHypersensitivity to the drugSpecial Precautions while taking Sodium citrate1. Renal impairment
2. Edema
3. Hypertension
4. Patients on a sodium restricted diet
5. Along with other medication
6. Addison`s disease
7. Type 2 diabetes mellitus
8. Chronic Diarrhea
9. Cardiac diseases
10. Toxemia of pregnancy
11. Urinary tract infections
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Sodium citrate1. Expectorant
2. Kidney stones
3. Cystitis
4. Gout
5. Urine and blood alkaliniser
6. Symptomatic treatment of nausea and vomiting
Interactions for Sodium citrateN/ATypical Dosage for Sodium citrateOral:
Expectorant: 0.3 to 1g
As alkaliniser: Dosage individualized and varies in different combinations Symptomatic treatment of nausea and vomiting: Use 5%Sodium citrate in the following doses:
Adults: 2 to3 g; 3 to 4 times daily.
Children (up to 3 months): 0.05 g;
Children (3 to 6 months): 0.1 g;
Children (6 to 12 months): 0.25 g;
Children (2 to 3 years): 0.30 g;
Children (4 to 7 years): 0.50 g;
Children (8 to 14 years): 1 to 2 g; 3 to 4 times daily
Schedule of Sodium citrateN/AStorage Requirements for Sodium citrateStore in a cool dry area in a tightly closed container. Protect from direct light, heat, and moistureEffects of Missed Dosage of Sodium citrateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sodium citrateProvide symptomatic treatment and supportive measures.Paracetamol
About ParacetamolAcetanilide derivative, Non narcotic Analgesic,Antipyretic.Mechanism of Action of ParacetamolParacetamol has analgesic and antipyretic action.
It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis.
Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect.
Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen.
Pharmacokinets of ParacetamolAbsorption: Paracetamol is rapidly and completely absorbed after oral administration.
Distribution: It is distributed mostly in the body in unbound form.
Metabolism: It is extensively metabolised in the liver.
Excretion: Excreted in the urine.
Onset of Action for Paracetamol30 - 60 minutesDuration of Action for Paracetamol6 hoursHalf Life of Paracetamol1-4 hoursSide Effects of Paracetamol1. Nausea
2. Abdominal distress
3. Allergic reactions
4. Rash
Contra-indications of Paracetamol1. Hypersensitivity to ParacetamolSpecial Precautions while taking Paracetamol1. Hepatic impairment
2. Renal impairment
3. Hypertension
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES : Contraindicated
Indications for Paracetamol1. To relieve pain and fever
2. Acute gout
3. Migraine
Interactions for ParacetamolCholestyramine: Reduces absorption of paracetamol.
Charcoal: Activated, administered immediately reduces absorption of paracetamol.
Domperidone and metochlopramide: Enhance absorption of paracetamol.
Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol.
Zidovudine: Effects zidovudine may be decreased.Typical Dosage for ParacetamolAdult:
500 - 1000 mg in 3 times daily
Maximum dose: 4 g / day
For migraine: 500 mg to be taken at the first sign of migraine attack and repeated 4 - 6 hourly until suppress mild attacks.
Children:
60 mg / kg body weight /day in 4 divided doses.
Schedule of ParacetamolHStorage Requirements for ParacetamolStore at 15-30 degree C in a tightly closed container. Protect from heat and moisture. Keep out of the reach of children.Effects of Missed Dosage of ParacetamolTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ParacetamolGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal. N-acetylcysteine is the specific antidote for Paracetamol poisoning. Dose: 150 mg /kg body weight as IV infusion over 15 minutes followed by same dose over 20 hours.
Maintenance dose: 75 mg / kg orally every 4 - 6 hours for 2 - 3 days. Haemodialysis can be done in emergency conditions.
Home Delivery for Chlorpheniramine Maleate + Sodium Citrate + Paracetamol in Your City
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Chlorpheniramine Maleate + Sodium Citrate + Paracetamol is a generic medicine name and there are several brands available for it. Some of the brands for chlorpheniramine maleate + sodium citrate + paracetamol might be better known than chlorpheniramine maleate + sodium citrate + paracetamol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chlorpheniramine maleate + sodium citrate + paracetamol in stock, you can ask for one of the branded alternatives for chlorpheniramine maleate + sodium citrate + paracetamol.
