Cefdinir Pharmacology

Cefdinir

About Cefdinir
Semisynthetic (Third Generation ) cephalosporin antibiotic, Oral broad-spectrum antibiotic.
Mechanism of Action of Cefdinir
Cefdinir is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefdinir inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefdinir
Pharmacokinets of Cefdinir
Absorption: Partially absorbed after oral administration, Distribution: Volume of distribution is greater for children than adults. Metabolism: The drug is not significantly metabolized inside the body. Excretion: Excreted mainly through urine

Onset of Action for Cefdinir
N/A
Duration of Action for Cefdinir
N/A
Half Life of Cefdinir
2 hours
Side Effects of Cefdinir
1.Rashes
2.Vaginitis
3.Pruritus
4.Candidiasis
5.Headache
6.Dizziness
7.Hypotension
8.Palpitation
9.Pseudo membranous colitis
10.Nausea
11.Vomiting
12.Diarrhea
13.Abdominal pain
14.Anorexia
15.Angioedema
Contra-indications of Cefdinir
1.Hypersensitivity to cephalosporins
2.Pseudo membranous colitis
Special Precautions while taking Cefdinir
1.Renal impairment
2.Patient allergic to Penicillins
3. Use cautiously along with antacids, anticoagulants, & along with other nephrotoxic drugs
Pregnancy Related Information
Contraindicated
Old Age Related Information
May be used.
Breast Feeding Related Information
Use with caution
Children Related Information
(Above 6 months): may be used
Indications for Cefdinir
1.Pneumonia
2.Bronchitis
3.Pharyngitis
4.Tonsillitis
5.Skin & soft tissue infections
6.Otitismedia
7.Sinusitis
Interactions for Cefdinir
Antacids: Cefdinir rate and extent of absorption is reduced in presence of antacid.
Probenecid: It inhibits renal excretion of cefdinir and may prolong plasma levels by competitively inhibiting renal tubular secretion.
Iron: Concomitant administration of cefdinir with therapeutic iron supplement reduces absorption.
Loop diuretics: Risk of nephrotoxicity may be increased.


Typical Dosage for Cefdinir
Adults: 0.3g twice daily
Children(above 6 months): 14 mg/kg/day twice daily
Maximum child dose: 600mg/day
Pneumonia, Bronchitis, Sinusitis, Otitismedia, Pharyngitis, Tonsillitis & Skin infections:
Adults:
0.3gm orally twice daily or 0.6mg once daily up to 10 days
Children above 6months:
7mg/kg twice daily or 14mg/kg once daily up to 10 days
Schedule of Cefdinir
H
Storage Requirements for Cefdinir
Store in a cool dry place.Protect from heat and light.Keep out of the reach of children.
Effects of Missed Dosage of Cefdinir
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Cefdinir
Symptoms of over dosage include Nausea, vomiting, diarrhea & some times siezures Treatment includes removal of drug from the body by dialysis & supportive measures

Home Delivery for Cefdinir in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cefdinir.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cefdinir and other medicines and health products. Home delivery services for cefdinir may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cefdinir only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cefdinir before they complete the sale. You can get this information while placing the order for cefdinir with the pharmacy.

Cefdinir is a generic medicine name and there are several brands available for it. Some of the brands for cefdinir might be better known than cefdinir itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefdinir in stock, you can ask for one of the branded alternatives for cefdinir.