Cefpirome Pharmacology

Cefpirome

About Cefpirome
A semisynthetic Fourth Generation Cephalosporin antibiotic, Parenteral antibiotic.
Mechanism of Action of Cefpirome
Cefpirome is a 4th generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefpirome inhibits the synthesis of polymer peptidoglycan of bacterial cell wall. Due to its zwitterions character it has better penetration through the porin channels of gram negative bacteria & it is more resistant to beta lactamase & rapidly binds to penicillin binding protein.
Pharmacokinets of Cefpirome
N/A
Onset of Action for Cefpirome
N/A
Duration of Action for Cefpirome
N/A
Half Life of Cefpirome
N/A
Side Effects of Cefpirome
1.Impairment of taste reception after injection
2.Rashes &allergic manifestations
3.Pseudo membranous colitis
4.Pain after I.M. injection & Thrombophlebitis after I.V. injection
5.Nausea
6.Vomiting
7.Diarrhoea
8.Eosinophilia
9.Thrombocytopenia
Contra-indications of Cefpirome
Hypersensitivity to Cephalosporins.
Special Precautions while taking Cefpirome
1.Renal impairment
2.Those allergic to penicillins
3.Use cautiously along with other nephrotoxic drugs like amino glycosides & loop diuretics


Pregnancy Related Information
Contraindicated.
Old Age Related Information
Use with caution.
Breast Feeding Related Information
Contraindicated.
Children Related Information
Use with caution
Below 12 years:contraindicated
Indications for Cefpirome
1.Pneumonia, Bronchitis & other lower respiratory tract infections
2.Resistant hospital acquired infections
3.Septicemia
4.Skin infections
5.Urinary tract infections
6.Infections in neutropenic patients.
Interactions for Cefpirome
Aminoglycosides: Monitor renal functions. False positive coomb?s test.
Typical Dosage for Cefpirome
Adults: 1g to 2gm I.M. or I.V. two times daily
Schedule of Cefpirome
H
Storage Requirements for Cefpirome
Store in a refrigerator.
Effects of Missed Dosage of Cefpirome
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Cefpirome
Give supportive measures and symptomatic treatment.

Home Delivery for Cefpirome in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cefpirome.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cefpirome and other medicines and health products. Home delivery services for cefpirome may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cefpirome only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cefpirome before they complete the sale. You can get this information while placing the order for cefpirome with the pharmacy.

Cefpirome is a generic medicine name and there are several brands available for it. Some of the brands for cefpirome might be better known than cefpirome itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefpirome in stock, you can ask for one of the branded alternatives for cefpirome.