Meropenem Pharmacology


About Meropenem
A synthetic, broad-spectrum carbapenem (beta-lactam) antibiotic.
Mechanism of Action of Meropenem
It binds to the penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis.
Pharmacokinets of Meropenem
Absorption: It is well absorbed after parenteral administration.Distribution: It is very widely distributed in the body.Metabolism: Only a very small amount undergo metabolism.Excretion: It is mainly excreted through urine.
Onset of Action for Meropenem
30 minutes
Duration of Action for Meropenem
1 day
Half Life of Meropenem
Side Effects of Meropenem
7.Steven Johnson syndrome
Contra-indications of Meropenem
1.Hypersensitive toMeropenum and other beta lactum antibiotic
Special Precautions while taking Meropenem
1.Renal impairment
2.Heart failure
4.Head injury
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Meropenem
3.Cystic fibrosis
6.Skin infection
Interactions for Meropenem
Probenecid competes with meropenem for active tubular secretion and thus inhibits the renal excretion of meropenem.
Typical Dosage for Meropenem
Adult :( IV bolus/infusion):0.5 - 1 g three times daily
Child: 60 - 120 mg/kg body weight /day in three divided dose
Schedule of Meropenem
Storage Requirements for Meropenem
Store at temperature in between 15 - 30 degree Celsius.

Effects of Missed Dosage of Meropenem
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Meropenem
Give supportive measures and symptomatic treatment.

Home Delivery for Meropenem in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including meropenem.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for meropenem and other medicines and health products. Home delivery services for meropenem may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take meropenem only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for meropenem before they complete the sale. You can get this information while placing the order for meropenem with the pharmacy.

Meropenem is a generic medicine name and there are several brands available for it. Some of the brands for meropenem might be better known than meropenem itself. If the pharmacy that's willing to deliver medicines to your home doesn't have meropenem in stock, you can ask for one of the branded alternatives for meropenem.