Dextrose 25% Pharmacology
Dextrose 25%
Dextrose injection undergoes oxidation to carbon dioxide and water. Water is an essential constituent of all body tissues Average normal adult requirement ranges from two to three liters. Water balance is maintained by various regulatory mechanisms. Water distribution depends primarily on the concentration of electrolytes in the body compartments.
2.Hyperglycaemia
3.Hyperosmotic syndrome (((mental confusion and loss of consciousness)))
4.Reactive hypoglycemia
5.Infection at the site of injection
6.Venous thrombosis
7.Extravasation
8.Hypervolemia.
2.Diabetic coma while patient is hyperglycemic
3.Intracranial haemorrhage
4.In the presence of delirium in dehydrated patients.
2.Ischemic stroke
3.Hypervolemia
4.Renal impairment
5,Urinary tract obstruction
6.Essential electrolytes, minerals, and vitamins should be supplied if needed
7.Potassium should be added to dextrose solutions administered to fasting patients with good renal function, especially those on digitalis therapy
8.Do not administer D50W if there is any doubt about IV patency.
NEONATES: use with caution
1.Hypoglycemia
2.Unconscious diabetic
3.Diagnostic tool in altered mental status of unknown etiology
4.Severe hypoglycemia
5.As a source of carbohydrate calories
6.Severe hyperkalemia
7.Dialysis-induced muscle cramps in uraemic patients
8.To promote diuresis.
ADULT:
Severe hypoglycaemia: 20 - 50 ml, repeat if needed
Severe hyperkalemia with ECG changes: 50 ml, repeat in 1 hour if finger stick glucose is less than 100 mg/dl
Dialysis induced muscle cramps: 50 ml and repeat in 5 minutes if there is no response
Acute attacks of porphyria: 40 ml/hour. If no improvement within 2 days alternative therapy should be considered.
CHILDREN below 3 years: 25% solution slow IV over 5 minutes
Severe hypoglycaemia: 0.5 - 1 g/kg/dose. Repeat as required.
Severe hyperkalemia with ECG changes: 0.5 g/kg/dose
Children above 3 years
Severe hypoglycemia: 1 - 2 ml/kg/dose, repeat if needed.
Severe hyperkalemia with ECG changes: 1 ml /kg/dose
NEONATES
Severe hypoglycaemia: loading dose 0.1 - 1.2 g/kg. Maintenance 5 - 7 mg/kg/min
Severe hyperkalemia with ECG changes: 0.5 g/kg/dose
Home Delivery for Dextrose 25% in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dextrose 25% and other medicines and health products. Home delivery services for dextrose 25% may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take dextrose 25% only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dextrose 25% before they complete the sale. You can get this information while placing the order for dextrose 25% with the pharmacy.
Dextrose 25% is a generic medicine name and there are several brands available for it. Some of the brands for dextrose 25% might be better known than dextrose 25% itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextrose 25% in stock, you can ask for one of the branded alternatives for dextrose 25%.
