Sulfamoxole Pharmacology


About Sulfamoxole
Intermediate-acting Sulfonamide, Antibiotic.
Mechanism of Action of Sulfamoxole
Sulfamoxole is an intermediate acting sulfonamide which exerts it`s bacteriostatic action by acting as an antimetabolite by inhibiting bacterial folic acid synthesis. Para amino benzoic acid (PABA) is a constituent of bacterial folic acid. Sulfonamides are structural analogues of PABA & thus inhibits enzyme bacterial
Folate synthetase. It competitively inhibits the union of PABA with pteridine residue to form dihydropteroic acid which conjugates with glutamic acid to produce dihydrofolic acid. Also being chemically similar to PABA the sulfonamides may itself incorporated to form an altered folate which is metabolically injurious
Pharmacokinets of Sulfamoxole
Absorption: Well absorbed orally, Distribution: Widely distributed, Metabolism: Acetylated in liver, Excretion: Excreted through urine.
Onset of Action for Sulfamoxole
Duration of Action for Sulfamoxole
8 to 12 hours
Half Life of Sulfamoxole
Side Effects of Sulfamoxole
4.Epigastric pain
7.Drug fever
8.Kernicterus in infants
17.Lumbar pain
Contra-indications of Sulfamoxole
1.Hypersensitivity to sulfonamides
2.Renal impairment
3.Hepatic impairment
Special Precautions while taking Sulfamoxole
1.Renal impairment
2.Hepatic impairment
3.Blood dyscrasias
4.G6PD deficiency
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Above 2 months: May be used
Neonates: Contraindicated
Indications for Sulfamoxole
5.Respiratory tract infections
6.Gastrointestinal tract infections
7.Urinogenitaltract infections
8.Skin infections
Interactions for Sulfamoxole
Typical Dosage for Sulfamoxole
Adults: 1gm orally twice daily for first day or first two days & then 500mg twice daily.
In severe infections: 1gm thrice daily
Children: Initial dose: 50 to 60mg/kg/day followed by 25 to 30 mg/kg thrice daily
Maximum dose: 75mg/kg/day
Schedule of Sulfamoxole
Storage Requirements for Sulfamoxole
Store at cool dry place. Keep out of the reach of children.
Effects of Missed Dosage of Sulfamoxole
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sulfamoxole
Give supportive measures and symptomatic treatment.

Home Delivery for Sulfamoxole in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sulfamoxole.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sulfamoxole and other medicines and health products. Home delivery services for sulfamoxole may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sulfamoxole only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sulfamoxole before they complete the sale. You can get this information while placing the order for sulfamoxole with the pharmacy.

Sulfamoxole is a generic medicine name and there are several brands available for it. Some of the brands for sulfamoxole might be better known than sulfamoxole itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sulfamoxole in stock, you can ask for one of the branded alternatives for sulfamoxole.