Teicoplanin Pharmacology


About Teicoplanin
Glycopeptide antibiotic, Antibiotic similar to vancomycin.
Mechanism of Action of Teicoplanin
Teicoplanin binds to the terminal dipeptide (amino D alanyl D alanine residue) sequence of peptidoglycan and inhibits the association and cross linking of peptidoglycan and as the result inhibit cell wall synthesis.
Pharmacokinets of Teicoplanin
Absorption: It is well absorbed after parenteral administration.
Distribution: It is very widely distributed in the body as plasma protein bound form.
Excretion: It is excreted through urine.
Onset of Action for Teicoplanin
30 minutes
Duration of Action for Teicoplanin
Half Life of Teicoplanin
1 week
Side Effects of Teicoplanin
1. Thrombophlebitis
2. Pain at the site of injection
3. Fever
4. Headache
5. Pruritis
6. Diarrhoea
7. Rashes
8. Nausea
9. Vomiting
10. Oototoxicity
11. Granulocytopenia
Contra-indications of Teicoplanin
1. Hypersensitive toTeicoplanin and other glycopeptides antibiotic.
Special Precautions while taking Teicoplanin
1. Renal impairment
2. History of allergy
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Use with caution
Indications for Teicoplanin
1. Endocarditis
2. Enterocolitis
3. Methicillin resistant Staphylococcus aureus infection
4. Neutropenic sepsis
5. Bone and joint infection
6. Skin and soft tissue infection
7. Lower respiratory tract infection
Interactions for Teicoplanin
Typical Dosage for Teicoplanin
Adult (IV dose): 400 mg 12 hourly for 3 doses followed by 400 mg once daily
Septic arthritis: 800 mg 12 hourly for 3 doses followed by 800 mg once daily.
Children : ( IV dose) 10 mg /kg body weight every 12 hours for 3 dose followed by 10 mg / kg body weight /day
Schedule of Teicoplanin
Storage Requirements for Teicoplanin
Store below 25 degree Celsius.
Effects of Missed Dosage of Teicoplanin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Teicoplanin
Give supportive measures and symptomatic treatment.

Home Delivery for Teicoplanin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including teicoplanin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for teicoplanin and other medicines and health products. Home delivery services for teicoplanin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take teicoplanin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for teicoplanin before they complete the sale. You can get this information while placing the order for teicoplanin with the pharmacy.

Teicoplanin is a generic medicine name and there are several brands available for it. Some of the brands for teicoplanin might be better known than teicoplanin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have teicoplanin in stock, you can ask for one of the branded alternatives for teicoplanin.