Linezolid Pharmacology


About Linezolid
Oxazolidinone derivative, reversible, nonselective monoamine oxidase inhibitor, Antibiotic.
Mechanism of Action of Linezolid
Linezolid binds to the 23 S fraction of 50 S ribosome and inhibit the formation of 70S initiation complex.
Pharmacokinets of Linezolid
Absorption: It is well absorbed after oral administration.Distribution: It is very widely distributed in the body.Metabolism:It is partly metabolized in the body.Excretion:It is excreted mainly through urine.
Onset of Action for Linezolid
Duration of Action for Linezolid
Half Life of Linezolid
4.5 - 5.5 hours
Side Effects of Linezolid
8.Tongue discolouration
9.Abdominal pain
10.Bowel upset
Contra-indications of Linezolid
Hypersensitivity to linezolid
Special Precautions while taking Linezolid
1.Renal impairment
2.Hepatic dysfunction
Pregnancy Related Information
Use with caution.
Old Age Related Information
May be used.
Breast Feeding Related Information
Use with caution.
Children Related Information
Indications for Linezolid
1.Skin and soft tissue infection
3.Wound infection
5.Respiratory tract infection
7.Vancomycin resistant enterococcal infection
Interactions for Linezolid
Typical Dosage for Linezolid
Adult: 800 - 1200 mg/day in two divided dose for 1 - 2 week
Schedule of Linezolid
Storage Requirements for Linezolid
It should be stored at room temperature. Keep away from heat and moisture.

Effects of Missed Dosage of Linezolid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.
Effects of Overdose of Linezolid
Give supportive measures and sumptomatic treatment.

Home Delivery for Linezolid in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including linezolid.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for linezolid and other medicines and health products. Home delivery services for linezolid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take linezolid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for linezolid before they complete the sale. You can get this information while placing the order for linezolid with the pharmacy.

Linezolid is a generic medicine name and there are several brands available for it. Some of the brands for linezolid might be better known than linezolid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have linezolid in stock, you can ask for one of the branded alternatives for linezolid.