Benzalkonium Chloride Pharmacology

Benzalkonium Chloride

About Benzalkonium Chloride
A nitrogenous cationic surfactant, Quaternary ammonium compound, Antiseptic,Disinfectant, A vaginal contraceptive spermicidal agent.
Mechanism of Action of Benzalkonium Chloride
The mechanism of bactericidal/microbicidal action is due to disruption of intermolecular interactions. This cause dissociation of cellular membrane bilayers, which compromises cellular permeability controls and induces leakage of cellular contents. Other biomolecular complexes within the bacterial cell can also undergo dissociation. It also inactivates the enzyme produced by different microorganisms. It also has spermicidal action. They work by damaging and killing sperm in the vagina. Therefore, the sperm are not able to travel from the vagina into the uterus and fallopian tubes, where fertilization usually takes place.
Pharmacokinets of Benzalkonium Chloride
Onset of Action for Benzalkonium Chloride
Duration of Action for Benzalkonium Chloride
Half Life of Benzalkonium Chloride
Side Effects of Benzalkonium Chloride
1. Chills
2. Confusion
3. Dizziness
4. Fever
5. Lightheadedness
6. Muscle aches
7. Sunburn-like skin rash
8. Cloudy or bloody urine
9. Increased frequency of urination
10. Pain in the bladder or lower abdomen
11. Pain on urination; thick
12. White or curd-like vaginal discharge-with use of cervical caps or diaphragms
13. Vaginal dryness
14. Odor
Contra-indications of Benzalkonium Chloride
1. Hypersensitivity to the drug
2. Allergies, irritations, or infections of the genitals
3. Recent abortion
4. Sores on the genitals (sex organs)
5. Irritation of the vagina
Special Precautions while taking Benzalkonium Chloride
Discontinue use if you have abnormal discharge or vaginal burning or itching.
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Benzalkonium Chloride
1. Antisepsis of skin, mucous membranes, and wounds.
2. Preoperative preparation of the skin, surgeons` hand and arm soaks
3. Treatment of wounds
4. Preservation of ophthalmic solutions
5. Irrigations of the eye, body cavities, bladder, urethra
6. Vaginal douching.
7. Contraceptives
Interactions for Benzalkonium Chloride
Typical Dosage for Benzalkonium Chloride
Vaginal suppositories dosage form (preventing pregnancy):
Adults and teenagers-
For use alone: One suppository inserted into the vagina at least ten minutes but not longer than four hours before each time you have sexual intercourse.
With a diaphragm: After the diaphragm with spermicide has been placed into the vagina, insert one suppository at least ten minutes, but not longer than four hours, before each time you have sexual intercourse. Also, insert another suppository before sexual intercourse if six hours have passed since you inserted the diaphragm
Schedule of Benzalkonium Chloride
Storage Requirements for Benzalkonium Chloride
Store at controlled room temperature, away from light and excessive heat. Keep out of reach of children.
Effects of Missed Dosage of Benzalkonium Chloride
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Benzalkonium Chloride

Home Delivery for Benzalkonium Chloride in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including benzalkonium chloride.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for benzalkonium chloride and other medicines and health products. Home delivery services for benzalkonium chloride may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take benzalkonium chloride only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for benzalkonium chloride before they complete the sale. You can get this information while placing the order for benzalkonium chloride with the pharmacy.

Benzalkonium Chloride is a generic medicine name and there are several brands available for it. Some of the brands for benzalkonium chloride might be better known than benzalkonium chloride itself. If the pharmacy that's willing to deliver medicines to your home doesn't have benzalkonium chloride in stock, you can ask for one of the branded alternatives for benzalkonium chloride.