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- Pharmacology For Cycloserine
CycloserineAbout CycloserineIsoxizolidone,d-alanine analogue, Anti TB antibiotic.Mechanism of Action of CycloserineCycloserine may be bactericidal or bacteriostatic depending on the concentration of the drug at the site of infection and the susceptibility of the organism towards the drug. Cycloserine is a D alanine analogue which is essential for peptidoglycan synthesis .It compete with D - alanine for two enzymes L- alanine racemase and D- alanyl alanine synthetase.These enzymes are required for incorporation of D- alanine in to peptidoglycan.These result in inhibition of cell wall formationPharmacokinets of CycloserineAbsorption: It is orally well absorbed after oral administration.Distribution: It is very widely distributed in the body.Metabolism: Only a very small amount undergoes metabolism.Excretion: It is excreted primarily through urine and also through faeces and breast milk.Onset of Action for Cycloserine0.5 - 1 hourDuration of Action for Cycloserine12 hourHalf Life of Cycloserine10 hourSide Effects of Cycloserine1. Skin rash
7. Loss of memory
10. Slurred speechContra-indications of Cycloserine1. Hypersensitivity to cycloserine
6. Chronic alcoholicsSpecial Precautions while taking Cycloserine1.Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Cycloserine1.Tuberculosis (Pulmonary &Extra pulmonary Tuberculosis),
2. Urinary tract infectionInteractions for CycloserineAlcohol: Incompatible, increase the possibility and risk of epileptic episodes.
Isoniazid: May result in increased cycloserine CNS side effects notably dizziness.
Typical Dosage for CycloserineAdult: 250 mg twice daily. The dose can be increased by 250 mg every 10 days. Maximum daily dose: 1 g
Children: 10 - 15 mg / kg body weight /day.
Schedule of CycloserineN/AStorage Requirements for CycloserineStore in a cool and dry place. Keep away from heat and moisture.Effects of Missed Dosage of CycloserineThe missed dose should be taken as soon as noticed and if it is the time to take the next dose then skip the missed dose.Effects of Overdose of CycloserineGive supportive measures and treatment. Gastric lavage has to be done. Seizure can be treated with Anticonvulsant and Pyridoxine.
Home Delivery for Cycloserine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cycloserine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cycloserine and other medicines and health products. Home delivery services for cycloserine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take cycloserine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cycloserine before they complete the sale. You can get this information while placing the order for cycloserine with the pharmacy.
Cycloserine is a generic medicine name and there are several brands available for it. Some of the brands for cycloserine might be better known than cycloserine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cycloserine in stock, you can ask for one of the branded alternatives for cycloserine.