Nystatin Pharmacology


About Nystatin
Polyene Antifungal.
Mechanism of Action of Nystatin
Nystatin is a fungicidal as well as a fungistatic drug. It has high affinity for ergosterol present in the fungal cell membrane and bind with it and they orients in such a way that micropore channel are formed and leads to efflux of ions, amino acid, sugar and other water soluble substances through this channel and results in cell disruption.
Pharmacokinets of Nystatin
Absorption: It is not orally absorbed.
Excretion: It is excreted in faeces.
Onset of Action for Nystatin
Duration of Action for Nystatin
1 day
Half Life of Nystatin
Side Effects of Nystatin
1. Nausea
2. Vomiting
3. Diarrhoea
4. Pruritis
5. Bad taste
Contra-indications of Nystatin
1. Hypersensitivity to Nystatin
Special Precautions while taking Nystatin
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Nystatin
1. Oral candidiasis
2. Cutaneous candidiasis
3. Mucocutaneous candidiasis
4. Monilial vaginitis
5. Monilial diarrhoea
6. Conjunctivitis
7. Corneal candidiasis
8. Candidiasis in immunocompromised patients
Interactions for Nystatin
Typical Dosage for Nystatin
Adult: 5 lac units every 8 hours in a day
Oral suspension:
Oropharyngeal candidiasis: 4 - 6 lac units four times daily
Oropharyngeal candidiasis in immunocompromised patients: 5 - 10 lac units 3 - 5 times daily
Cutaneous or Mucocutaneous candidiasis: Topical use: Apply to the affected part 2 - 3 times daily for 2 week
Vaginal candidiasis:
Vaginal use (tablets): Insert 1 lac units in to vagina 1- 2 times daily for 2 weeks
Oral suspension:
1 - 2 lac units four times daily
Schedule of Nystatin
Storage Requirements for Nystatin
The drug should be stored at 15 - 30 degree C.Protect away from heat and light.
Effects of Missed Dosage of Nystatin
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Nystatin
Give supportive measures.

Home Delivery for Nystatin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including nystatin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for nystatin and other medicines and health products. Home delivery services for nystatin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take nystatin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for nystatin before they complete the sale. You can get this information while placing the order for nystatin with the pharmacy.

Nystatin is a generic medicine name and there are several brands available for it. Some of the brands for nystatin might be better known than nystatin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have nystatin in stock, you can ask for one of the branded alternatives for nystatin.