NaCl 0.45% Pharmacology

NaCl 0.45%

About NaCl 0.45%
IV solutions ;It is given along with dextrose solution, A nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply.
Mechanism of Action of NaCl 0.45%
This solution of sodium chloride in sterile water (contains Na+ and Cl-) create an oncotic gradient for expanding plasma volume. Then a greater percentage of the infused fluid stays within the vascular space and does not leak out into the extra vascular spaces. It would be available to rapidly rehydrate the extra vascular volumes in the extracellular fluid (ECF) and intracellular fluid (ICF) spaces.
It is a nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply.It is given along with dextrose solution.
0.45% Sodium Chloride Injection contains 4.5 g/L Sodium Chloride, (NaCl) with an osmolarity of 154 mOsmol/L .It contains 77 mEq/L sodium and 77 mEq/L chloride
Pharmacokinets of NaCl 0.45%
N/A
Onset of Action for NaCl 0.45%
N/A
Duration of Action for NaCl 0.45%
N/A
Half Life of NaCl 0.45%
N/A
Side Effects of NaCl 0.45%
1. Pulmonary edema
2. Febrile reactions
Contra-indications of NaCl 0.45%
Contraindicated in patients with hypersensitivity to the solution
Special Precautions while taking NaCl 0.45%
1.Severe renal insufficiency
2.Congestive heart failure
3.Do not use plastic containers in series connections
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for NaCl 0.45%
1. Intravenous infusion
2. Severe salt depletion
3. Low salt syndrome which may occur in presence of heart failure, renal impairment, during surgery, etc.
4. Excessive fluid loss due to sweating, vomiting, diarrhoea, etc
Interactions for NaCl 0.45%
N/A
Typical Dosage for NaCl 0.45%
Dose is dependent upon the age, weight and clinical condition of the patient.
Schedule of NaCl 0.45%
N/A
Storage Requirements for NaCl 0.45%
Store at room temperature (25 - 30 degree C)
Effects of Missed Dosage of NaCl 0.45%
N/A
Effects of Overdose of NaCl 0.45%
Give symptomatic and supportive treatment

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