Arteether Pharmacology

Arteether

About Arteether

Semi synthetic derivative of artemisinine, Fast acting blood schizontocide, Anti malarial.

Mechanism of Action of Arteether

It is a schizonticidal drug. The endoperoxide bridges in Artemether are cleaved by the binding of haeme and liberate highly active free radicals. These radicals bind to membrane proteins and cause lipid peroxidation and damages endoplasmic reticulum. It also inhibits protein synthesis and lysis of the parasite.

Pharmacokinets of Arteether

Absorption: Artemether is orally well absorbed. Distribution: It is distributed in plasma protein bound form. Metabolism: It is metabolised in the liver to active dihydro artemisnin

Onset of Action for Arteether

N/A

Duration of Action for Arteether

N/A

Half Life of Arteether

1 - 2 days

Side Effects of Arteether

1.Nausea
2.Vomiting
3.Diarrhoea
4.Abdominal pain
5.Reduction in eosinophil count

Contra-indications of Arteether

1.Hypersensitivity to Arteether and other artemisnin derivative

Special Precautions while taking Arteether

1.Renal impairment
2.Hepatic impairment
3.Cardiac failure
4.Monitor patients on concomitant use of drugs which cause prolongation of QT intervals

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution

Indications for Arteether

Chloroquine resistant malaria, complicated falciparum malaria and cerebral malaria.

Interactions for Arteether

N/A

Typical Dosage for Arteether

Adult (IM): 150 mg once daily for 3 days
Children (IM): 3mg/kg body weight /day for 3 days

Schedule of Arteether

Storage Requirements for Arteether

Store in a cool dark place. Keep out of the reach of children.

Effects of Missed Dosage of Arteether

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.

Effects of Overdose of Arteether

Give supportive measures and symptomatic treatment.

Home Delivery for Arteether in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including arteether.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for arteether and other medicines and health products. Home delivery services for arteether may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take arteether only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for arteether before they complete the sale. You can get this information while placing the order for arteether with the pharmacy.

Arteether is a generic medicine name and there are several brands available for it. Some of the brands for arteether might be better known than arteether itself. If the pharmacy that's willing to deliver medicines to your home doesn't have arteether in stock, you can ask for one of the branded alternatives for arteether.