Adefovir Pharmacology

Adefovir

About Adefovir
Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)
Mechanism of Action of Adefovir
Adefovir undergoes phosphorylation in the presence of cellular kinase enzyme to Adefovir diphosphate. This Adefovir diphosphate competitively inhibits HBV DNA polymerase and reverse transcriptase enzyme by competing with nucleoside adenosine triphosphate and inhibits DNA synthesis.
Pharmacokinets of Adefovir
Absorption: It is absorbed after oral administration. Distribution: It is distributed in the body. Excretion: It is excreted mainly through urine.
Onset of Action for Adefovir
N/A
Duration of Action for Adefovir
N/A
Half Life of Adefovir
8 hour
Side Effects of Adefovir
1.Asthenia
2.Headache
3.Nausea
4.Diarrhoea
5.Abdominal pain
6.Flatulance
7.Dyspepsia
8.Fever
9.Rash
10.Increase in liver enzyme
Contra-indications of Adefovir
Hypersensitivity to Adefovir
Special Precautions while taking Adefovir
1.Renal impairment
2.Hepatic impairment
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
NEONATES: contraindicated
Indications for Adefovir
1.Hepatitis B infection
Interactions for Adefovir
N/A
Typical Dosage for Adefovir
Adult: 10 mg / day
Schedule of Adefovir
H
Storage Requirements for Adefovir
The drug should be kept at 15 - 30 degree C in a tightly closed container. Protect away from heat and light. Keep out of the reach of children.
Effects of Missed Dosage of Adefovir
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Adefovir
Give supportive measures and treatment

Home Delivery for Adefovir in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including adefovir.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for adefovir and other medicines and health products. Home delivery services for adefovir may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take adefovir only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for adefovir before they complete the sale. You can get this information while placing the order for adefovir with the pharmacy.

Adefovir is a generic medicine name and there are several brands available for it. Some of the brands for adefovir might be better known than adefovir itself. If the pharmacy that's willing to deliver medicines to your home doesn't have adefovir in stock, you can ask for one of the branded alternatives for adefovir.