Piperazine Pharmacology

Piperazine

About Piperazine
A GABA receptor agonist, Anthelmintic -Antinematodal.
Mechanism of Action of Piperazine
The drug exerts its action by acting as a GABA agonist and causing hyperpolarisation of worm muscle and relaxation and depresses the contractile action of acetyl choline resulting in flaccid paralysis of worms, which are then expelled by peristaltic movements
Pharmacokinets of Piperazine
Absorption: The drug is absorbed orally, Metabolism: The drug undergoes partial metabolism inside the body, Excretion: Excreted through urine.
Onset of Action for Piperazine
N/A
Duration of Action for Piperazine
N/A
Half Life of Piperazine
N/A
Side Effects of Piperazine
1.Nausea
2.Vomiting
3.Gastrointestinal disturbances
4.Urticaria
5.Dizziness
6.Seizures
7.Headache
Contra-indications of Piperazine
1.Hypersensitivity to the drug
2.Renal impairment
3.Epilepsy
Special Precautions while taking Piperazine
1.Hepatic impairment:
2.Neurological disorders
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Piperazine
1. Ascariasis
2. Enterobiasis
Interactions for Piperazine
N/A
Typical Dosage for Piperazine
Ascariasis:
Adults: 4gm once daily for two days
Children: 0.75 gm/year of age up to 4gm
Enterobiasis:
75mg/kg up to 4gm as s single dose or 50mg/kg up to 2gm/day for a week
Schedule of Piperazine
W
Storage Requirements for Piperazine
Store at room temperature in a light resistant tightly closed container
Effects of Missed Dosage of Piperazine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Piperazine
Treatment is supportive and symptomatic.

Home Delivery for Piperazine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including piperazine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for piperazine and other medicines and health products. Home delivery services for piperazine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take piperazine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for piperazine before they complete the sale. You can get this information while placing the order for piperazine with the pharmacy.

Piperazine is a generic medicine name and there are several brands available for it. Some of the brands for piperazine might be better known than piperazine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have piperazine in stock, you can ask for one of the branded alternatives for piperazine.