Distribution: It is widely distributed in the body tissues and fluid. Naloxone crosses the placenta.
Metabolism: Naloxone undergoes metabolism in the liver mainly by glucuronide conjugation.
Excretion: It is excreted mainly in the urine.
2.Patient on Opioid therapy
3.Acute opioid withdrawal
2.Opioid-induced respiratory depression
Neonatal Opiate Depression: 0.01 mg/kg, administered into the umbilical vein of the neonate at 2- to 3-minute intervals until the desired response is obtained. If required doses may be repeated at 1- 2 hour intervals depending on the response of the neonate and the dosage and duration of action of the opiate administered to the mother. When the IV route cannot be used, the drug may be administered by IM or subcutaneous injection.
Adult: 0.4-2 mg IV, administered at 2- to 3-minute intervals if necessary.
Children: 0.01 mg/kg; if this dose does not produce the desired degree of response, a subsequent dose of 0.1 mg/kg may be administered.
Opiate addiction (oral): 200 mg to 3 g daily.
Home Delivery for Naloxone in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including naloxone.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for naloxone and other medicines and health products. Home delivery services for naloxone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take naloxone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for naloxone before they complete the sale. You can get this information while placing the order for naloxone with the pharmacy.
Naloxone is a generic medicine name and there are several brands available for it. Some of the brands for naloxone might be better known than naloxone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have naloxone in stock, you can ask for one of the branded alternatives for naloxone.