Distribution- Widely distributed in the body.4% bound to the plasma proteins
Metabolism- It is metabolized in the tissues by alkaline phosphatase (which causes dephosphorylation of drug). Its active metabolite is Thiol and inactive metabolite is Disulfide
Excretion- Excreted through urine
3.Flushing (feeling of warmth)
4.Chills ( feeling of coldness)
9.Shortness of breath
15.Swelling of the throat
2. Low blood pressure
4. Renal impairment
5. Hepatic impairment
2. Cerebrovascular diseases.
3. Antihypertensive drug should be stopped 24 hrs before administration
4. Antiemetics should be administered before infusion
2. Myelodysplastic syndromes
3.Reduction of cumulative nephrotoxicity due to Cisplatin
740-910mg/metre square once daily over 15 min, Drug to be taken 30min before starting chemotherapy treatment
Prevention of Xerostomia: 200mg / metre square once daily over 3 minutes, starting 15- 30 minutes before radiotherapy.
Home Delivery for Amifostine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including amifostine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for amifostine and other medicines and health products. Home delivery services for amifostine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take amifostine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for amifostine before they complete the sale. You can get this information while placing the order for amifostine with the pharmacy.
Amifostine is a generic medicine name and there are several brands available for it. Some of the brands for amifostine might be better known than amifostine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amifostine in stock, you can ask for one of the branded alternatives for amifostine.