Distribution-This hydrophilic drug does not enter to the tissues.10% bound to the plasma proteins.
Metabolism- It is metabolized into its inactive metabolites i.e.dimesna (mesna disulfide) by oxidation during circulation.
Excretion-Excreted via urine as parent drug (35%) and its metabolite (33%)
3. Soft stool
8. Blood in urine
9. Skin rash
14. Limp pain
2. Engaging in activities which require alertness such as driving or using machinery
2. Toxicity to the urinary passage caused by oxazaphosphorins such as ifosamide
Adults-Mesna dose depend upon the amount of ifosfamide and cyclophosphamide that a patient receives. The standard dose depends equal to 20% of the total ifosfamide given at three separate time interval through a vein infused over at least 5 minute, first dose is right before the ifosfamide, often referred to as 0 hr, the 2nd dose is 4 hr after the start of the infusion and the 3rd dose is 8 hrs after the start of infusion.
Mesna can also be administered through orally by mixing with flavoured drink like grape juice, cola, chocolate and milk etc.
Home Delivery for Mesna in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including mesna.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for mesna and other medicines and health products. Home delivery services for mesna may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take mesna only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for mesna before they complete the sale. You can get this information while placing the order for mesna with the pharmacy.
Mesna is a generic medicine name and there are several brands available for it. Some of the brands for mesna might be better known than mesna itself. If the pharmacy that's willing to deliver medicines to your home doesn't have mesna in stock, you can ask for one of the branded alternatives for mesna.