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- Pharmacology For Terazosin
TerazosinAbout TerazosinA selective alpha 1 adrenergic antagonist, Antihypertensive.Mechanism of Action of TerazosinThe drug exerts its antihypertensive action by acting as a selective alpha-1 antagonist. It dilates both arteries and veins, thus it reduces total peripheral resistance, reduce blood pressure, & reduce venous return and cardiac output. The alpha-1 blockade in non vascular smooth muscles cause relaxation of smooth muscles of prostate, internal sphincter of the bladder etc. thus decrease the resistance to urinary outflow in patients with benign prostatic hypertrophy. It decrease the tone of prostatic and bladder neck muscles and relaxes bladder trigone, prostate, and prostatic urethra; reduces dynamic obstruction, increases urinary flow rate, causing more complete emptying of bladder. It also induces apoptosis in prostate smooth muscle cells The drug decreases LDL cholesterol & increases HDL cholesterol.Pharmacokinets of TerazosinAbsorption: It is well absorbed orally, Distribution: Widely distributed in a highly plasma protein bound form, Metabolism: It is metabolized in liver
Excretion: Excreted mainly through bile and faeces
Onset of Action for Terazosin15minutsDuration of Action for Terazosin18 to 24 hoursHalf Life of Terazosin12hoursSide Effects of Terazosin1.Postural hypotension
5.Dryness of mouth
Contra-indications of TerazosinHypersensitivity to the drugSpecial Precautions while taking Terazosin1.Renal impairment
4.Started with low dose usually given at bed time
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationContraindicatedIndications for Terazosin1.Hypertension
2.Benign prostatic hypertrophy
Interactions for TerazosinClonidine: The antihypertensive effects of clonidine may be decreased.Typical Dosage for TerazosinHypertension: Starts with 1mg at bed time, then gradually increase at 1week intervals up to 10mg/day based on patient`s response
Maximum daily dose: 20mg
Benign prostatic hypertrophy: Starts with 1mg at bed time, then gradually increase at 1week intervals up to10mg/day
Maximum daily dose: 10mg
Schedule of TerazosinHStorage Requirements for TerazosinStore at room temperature in a light resistant tightly closed container
Effects of Missed Dosage of TerazosinTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of TerazosinTreatment is supportive and symptomatic. After ingestion empty the stomach by induced emesis and gastric lavage. Administer activated charcoal
Home Delivery for Terazosin in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including terazosin.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for terazosin and other medicines and health products. Home delivery services for terazosin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take terazosin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for terazosin before they complete the sale. You can get this information while placing the order for terazosin with the pharmacy.
Terazosin is a generic medicine name and there are several brands available for it. Some of the brands for terazosin might be better known than terazosin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have terazosin in stock, you can ask for one of the branded alternatives for terazosin.