- Medicine India
- Generic Medicines
- Pharmacology For Dihydralazine sulphate
Dihydralazine sulphate Pharmacology
Dihydralazine sulphateAbout Dihydralazine sulphateA pyridazine antiadrenergic agent, Nonsympatholytic vasodilatory antihypertensives.Mechanism of Action of Dihydralazine sulphateDihydralazine is an antihypertensive and its actions are similar to Hydralazine.Hydralazine exerts its pharmacological actions by direct vasodilator action on arteriolar smooth muscles with little actions on venous capacitance vessels. It produces after load reduction by dilating resistance vessels which leads to decreasing aortic impedence.So that more blood is pumped even in weaker ventricular contractions. It decreases total peripheral resistance and there is greater decrease in diastolic pressure than systolic pressure. There is a decrease in intracellular Ca2+concentration but there is no reduction in renal blood flow.Pharmacokinets of Dihydralazine sulphateAbsorption: It is well absorbed orally, but bioavailability is low in fast acetylators.Distribution: Widely distributed in a highly plasma protein bound form.Metabolism: It is metabolized in liver,plasma and gastrointestinal mucosa. Excretion: Excreted mainly through urine and the rest of dose is excreted through bile and faeces.
Onset of Action for Dihydralazine sulphateN/ADuration of Action for Dihydralazine sulphateN/AHalf Life of Dihydralazine sulphateN/ASide Effects of Dihydralazine sulphate1. Tachycardia
6. Dryness of mouth
7. Nasal congestion
11. Orthostatic hypotension
14. Sleep disturbances
15. Reversible lupus erythmatosis
18. Muscle cramps
Contra-indications of Dihydralazine sulphate1. Hypersensitivity to the drug
2. Ischaemic heart disease
3. Coronary artery diseases
4. Valvular stenosis
6. Aortic aneurism
Special Precautions while taking Dihydralazine sulphate1. Renal impairment
2. Hepatic impairment
3. Cardiovascular disorders
4. Cerebro vascular disorders
5. Use with caution along with other antihypertensive drugs
6. Slowly withdraw the drug with caution
Pregnancy Related InformationUse with cautionOld Age Related InformationContraindicatedBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Dihydralazine sulphate1. Hypertension
2. Congestive heart failure
Interactions for Dihydralazine sulphateN/ATypical Dosage for Dihydralazine sulphateAs directed by the physicianSchedule of Dihydralazine sulphateHStorage Requirements for Dihydralazine sulphateStore at controlled room temperature at a temperature range of 15 to 30 degree C in a light resistant tightly closed container.Effects of Missed Dosage of Dihydralazine sulphateTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.Effects of Overdose of Dihydralazine sulphateTreatment is supportive and symptomatic. After ingestion empty the stomach by induced emesis and gastric lavage. Administer activated charcoal to reduce absorption.
Home Delivery for Dihydralazine sulphate in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dihydralazine sulphate.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dihydralazine sulphate and other medicines and health products. Home delivery services for dihydralazine sulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take dihydralazine sulphate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dihydralazine sulphate before they complete the sale. You can get this information while placing the order for dihydralazine sulphate with the pharmacy.
Dihydralazine sulphate is a generic medicine name and there are several brands available for it. Some of the brands for dihydralazine sulphate might be better known than dihydralazine sulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dihydralazine sulphate in stock, you can ask for one of the branded alternatives for dihydralazine sulphate.