It increases exercise tolerance and reduce myocardial oxygen demand in angina patients. It acts as a coronary artery dilator inhibits coronary artery spasm and improves coronary blood flow. It interferes with depolarization and decreases SA node automaticity. It prolongs AV nodal effective refractory period and increases PR interval. It decreases heart rate and increases cardiac out put. It markedly relaxes arterioles and milder effects on veins. It do not compromise haemodynamics and cerebral and renal perfusion.
Distribution: Widely distributed in a protein bound form.
Metabolism: Metabolized in liver, and there is active metabolite.
Excretion: Excreted through urine.
Oral: 2 to 4 hours
8. A-V block
2. 2nd and 3rd degree Heart block
3. Sick sinus syndrome
4. Hypersensitivity to the drug
5. Unstable angina
6. Hepatic impairment
7. Renal impairment
3. Impaired left ventricular function
4. Congestive heart failure
5. Use cautiously along with other antihypertensive drugs
6. Use with caution along with digitalis and other antiarrythmic drugs
7. Slowly withdraw the drug with caution
8. Diabetes mellitus
9. Long term use
2. Prinzmetal`s angina
3. Stable angina
?-Blockers: Though advantageous in some, concomitant use may result in increased adverse effects like bradycardia and conduction disturbances.
Carbamazepine, Cyclosporin, Digitalis Glycosides: Efficacy of these drugs increased with possible toxicity.
Theophylline: Increased efficacy of theophylline.
Prinzmetal`s angina and Stable angina: 120 to 180mg/day. Single or in 3 to 4 divided doses.
Maximum dose: 360mg/day.
Hypertension: 120 to 240mg/day. Single or in 3 to 4 divided doses.
Maximum dose: 360mg/day.
Home Delivery for Diltiazem in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including diltiazem.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for diltiazem and other medicines and health products. Home delivery services for diltiazem may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take diltiazem only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for diltiazem before they complete the sale. You can get this information while placing the order for diltiazem with the pharmacy.
Diltiazem is a generic medicine name and there are several brands available for it. Some of the brands for diltiazem might be better known than diltiazem itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diltiazem in stock, you can ask for one of the branded alternatives for diltiazem.