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- Pharmacology For Trimetazidine
TrimetazidineAbout TrimetazidineCytoprotective,vasodilator, Anti-ischemic (anti-anginal) agent.Mechanism of Action of TrimetazidineIt is a cytoprotective drug which reduces anginal attacks and improves exercise tolerance by nonhaemodynamic mechanisms. It improves cellular tolerance to ischaemia by: - 1) Inhibiting mitochondrial long chain 3-ketoacyl-CoA-thiolase; a key enzyme in fatty acid oxidation and there by reducing fatty acid metabolism and increasing glucose metabolism in myocardium. 2) Limiting intracellular acidosis and sodium and calcium accumulation during ischaemia. 3) Protecting against O* free radical induced membrane damagePharmacokinets of TrimetazidineAbsorption: It is absorbed orally. Metabolism: Partly metabolized in the body. Excretion: Most of the drug excreted unchanged in urine.Onset of Action for TrimetazidineWithin 60minutesDuration of Action for Trimetazidine6 to 8 hoursHalf Life of Trimetazidine6 hoursSide Effects of Trimetazidine1.Gastric burning
Contra-indications of TrimetazidineHypersensitivity to the drugSpecial Precautions while taking TrimetazidineN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Trimetazidine1.Angina pectoris
Interactions for TrimetazidineN/ATypical Dosage for Trimetazidine20mg thrice daily
Schedule of TrimetazidineHStorage Requirements for TrimetazidineStore at room temperature at a range of 15 to 30 degree C. Protect from light, heat, and moisture.Effects of Missed Dosage of TrimetazidineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of TrimetazidineProvide symptomatic treatment and supportive measures.
Home Delivery for Trimetazidine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including trimetazidine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for trimetazidine and other medicines and health products. Home delivery services for trimetazidine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take trimetazidine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for trimetazidine before they complete the sale. You can get this information while placing the order for trimetazidine with the pharmacy.
Trimetazidine is a generic medicine name and there are several brands available for it. Some of the brands for trimetazidine might be better known than trimetazidine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have trimetazidine in stock, you can ask for one of the branded alternatives for trimetazidine.