Nadroparin Pharmacology


About Nadroparin
Low Molecular Weight Heparin, Anticoagulant.
Mechanism of Action of Nadroparin
Nadroparin is an anticoagulant. It is a low molecular weight heparin that binds to and accelerates the activity of antithrombin III. This produces inactivation of factor Xa and thrombin and prevents the formation of blood clots. Binding of Nadroparin with Heparin cofactor II also inhibits thrombin activity and produces anticoagulant effect.
It is used in the treatment and prophylaxis of venous thromboembolism and to prevent clotting during extracorporeal circulation. It is also used in the management of unstable angina.
Pharmacokinets of Nadroparin
Absorption: It is well absorbed after subcutaneous injection.
Onset of Action for Nadroparin
Duration of Action for Nadroparin
Half Life of Nadroparin
3.5 hours
Side Effects of Nadroparin
4.Mild pain, redness, or warmth at the injection site
5.Difficulty in breathing
6.Closing of throat
7.Swelling of lips, tongue, or face; or hives
8.Prolonged bleeding
9.Pain, warmth, or redness in an arm or leg
10.Ulceration at the injection site.
Contra-indications of Nadroparin
1.Hypersensitivity to Nadroparin
2.Uncontrolled active bleeding
3.Allergy to pork products
Special Precautions while taking Nadroparin
1.Bacterial endocarditis
2.Uncontrolled blood pressure
3.Need to have surgery or another invasive procedure
5.Stomach ulcer
6.Eye problems due to diabetes or high blood pressure
7.Liver disease
8.Kidney disease
9.Very low level of platelets
10.Cannot have accurate blood testing done prior to and during dosing
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Nadroparin
1.Deep vein thrombosis
2.Pulmonary embolism
3.Prevent clotting
Interactions for Nadroparin
Typical Dosage for Nadroparin
Prophylaxis and Treatment of Thromboembolic Disorders: SC injection of 2 850 anti-Xa IU (0.3 mL). The first dose should be given 2 to 4 hours before surgery. Treatment should continue for at least 7 days.
Prophylaxis in Orthopedic Surgery: 38 anti-Xa IU/kg administered 12 hours before and 12 hours after surgery and repeat the same dose once daily for 2 days and 57 anti-Xa IU/kg administered on day 4. Treatment should continue for at least 10 days.

Schedule of Nadroparin
Storage Requirements for Nadroparin
Store at room temperature away from moisture and heat.Keep out of the reach of children. Keep the medicine from freezing. Do not refrigerate.
Effects of Missed Dosage of Nadroparin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.
Effects of Overdose of Nadroparin
Give supportive measures and symptomatic treatment.Bleeding can be stopped by discontinuing the drug and by applying pressure at the site.Protmine sulfate can also be administered if needed.

Home Delivery for Nadroparin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including nadroparin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for nadroparin and other medicines and health products. Home delivery services for nadroparin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take nadroparin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for nadroparin before they complete the sale. You can get this information while placing the order for nadroparin with the pharmacy.

Nadroparin is a generic medicine name and there are several brands available for it. Some of the brands for nadroparin might be better known than nadroparin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have nadroparin in stock, you can ask for one of the branded alternatives for nadroparin.