Tirofiban Pharmacology


About Tirofiban
Non peptide Glycoprotein IIb/IIIa inhibitor, Antiplatelet agent.
Mechanism of Action of Tirofiban
Tirofiban is an antiplatelet drug. It is glycoprotein IIb / IIIa inhibitors. It is a reversible antagonist of fibrinogen binding to the glycoprotein IIb / IIIa receptor, the major platelet surface receptor involved in platelet aggregation. Tirofiban works by preventing platelets aggregation. Sticking of platelets each other produces blood clots
Pharmacokinets of Tirofiban
Absorption: It is absorbed after parenteral administration
Distribution: It is distributed mainly in protein binding.
Metabolism: It undergoes insignificant metabolism.
Excretion: It is excreted mainly in urine and small amount in faeces
Onset of Action for Tirofiban
Duration of Action for Tirofiban
Half Life of Tirofiban
2 hours
Side Effects of Tirofiban
3.Leg pain
5.Pelvic pain
7.Bleeding on local sites
12.Difficulty urinating
13.Slow heartbeat
Contra-indications of Tirofiban
Hypersensitivity to Tirofiban
Special Precautions while taking Tirofiban
1.Hepatic impairment
2.Renal impairment
3.History of bleeding
4.Arteriovenous malformation
8.Acute pericarditis
10.Severe anemia
13.Cerebrovascular disease
14.Hemorrhagic retinopathy
15.Chronic hemodialysis
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Indications for Tirofiban
1.Unstable angina
2.Myocardial infarction
Interactions for Tirofiban
Typical Dosage for Tirofiban
Adult: 0.4 ?g / kg /minute for 30 minutes. Then the rate is decreased to 0.1 ?g /kg /minute
Schedule of Tirofiban
Storage Requirements for Tirofiban
Store at 25 degree C. Do not freeze. Protect from heat and light.
Effects of Missed Dosage of Tirofiban
Take the missed dose as soon a noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Tirofiban
Give supportive measures and symptomatic treatment.

Home Delivery for Tirofiban in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including tirofiban.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for tirofiban and other medicines and health products. Home delivery services for tirofiban may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take tirofiban only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tirofiban before they complete the sale. You can get this information while placing the order for tirofiban with the pharmacy.

Tirofiban is a generic medicine name and there are several brands available for it. Some of the brands for tirofiban might be better known than tirofiban itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tirofiban in stock, you can ask for one of the branded alternatives for tirofiban.