Cardioplegia Pharmacology

Cardioplegia

About Cardioplegia
N/A
Mechanism of Action of Cardioplegia
It temporarily stops heart for cardiac surgery; induce cardiac arrest using drug and assisted by cold. Thus causes cold-ischaemic Cardioplegia. Potassium (K+) ion concentration is responsible for prompt cessation of mechanical myocardial contractile activity.
Pharmacokinets of Cardioplegia
N/A
Onset of Action for Cardioplegia
N/A
Duration of Action for Cardioplegia
N/A
Half Life of Cardioplegia
N/A
Side Effects of Cardioplegia
1.Arrhythmias
2.Ventricular fibrillation
3.Myocardial infarction
4.Delayed recovery
5.Absence of recovery
Contra-indications of Cardioplegia
Do not use intravenously.
Special Precautions while taking Cardioplegia
1.Physicians familiar with the cardiac surgery should only use this drug,
2.Monitor ECG continuously during the procedure,
3.Use appropriate equipment for defibrillation and inotropic drugs during post operative recovery,
4.Do not administer unless solution is clear and container is undamaged. Discard unused portion.
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Contraindicated
Indications for Cardioplegia
1.Open heart surgery
2.Cardiopulmonary bypass surgery
Interactions for Cardioplegia
N/A
Typical Dosage for Cardioplegia
20ml of the drug is diluted using 1litre Ringer`s solution. Administer the cooled solution in to the aortic root at a rate of 300ml/m2 surface area/minute three times initially after cardio pulmonary bypass institution and cross clamping of the ascending aorta. Keep hypothermia by external cardiac cooling and also keep the solution always cold. Repeat the administration in every half an hour, or sooner when signs of cardiac activity are returning or when myocardial temperature reaches 180C.
Schedule of Cardioplegia
N/A
Storage Requirements for Cardioplegia
Store at a temperature below 25 degree C in a cool dry place.
Effects of Missed Dosage of Cardioplegia
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Cardioplegia
Treatment is supportive and symptomatic. Defibrillation by electric shock may be required to restore normal cardiac function. Use appropriate instrument and inotropic drug as required.

Home Delivery for Cardioplegia in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cardioplegia.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cardioplegia and other medicines and health products. Home delivery services for cardioplegia may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cardioplegia only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cardioplegia before they complete the sale. You can get this information while placing the order for cardioplegia with the pharmacy.

Cardioplegia is a generic medicine name and there are several brands available for it. Some of the brands for cardioplegia might be better known than cardioplegia itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cardioplegia in stock, you can ask for one of the branded alternatives for cardioplegia.