Pitavastatin Pharmacology


About Pitavastatin
Statins ,HMG-CoA reductase inhibitor, Hypolipidemic.
Mechanism of Action of Pitavastatin
Pitovastatin is a new member of statins. It competitively inhibits the conversion of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. The drug exerts its action by specific inhibition of enzyme; 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG CoA reductase) and reduces cholesterol synthesis up to 50% at therapeutic doses. This results in compensatory increase in low density lipoprotein (LDL) receptor expression in liver which ultimately leads to increased receptor mediated uptake and catabolism of intermediate density lipoprotein(IDL) and low density lipoprotein (LDL). It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein (VLDL) and lowers plasma triglyceride levels. It increases high density lipoprotein (HDL) levels.
Pharmacokinets of Pitavastatin
Absorption: It is readily absorbed after oral administration.
Onset of Action for Pitavastatin
Duration of Action for Pitavastatin
Half Life of Pitavastatin
Side Effects of Pitavastatin
3.Abdominal discomfort
4.Heart burn
5.Abdominal pain
10.Blurred vision
11.Abnormal liver function tests
15.Muscle cramps
Contra-indications of Pitavastatin
Hypersensitivity to the drug
Special Precautions while taking Pitavastatin
1.Renal impairment
2.Hepatic impairment

Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Indications for Pitavastatin
Interactions for Pitavastatin
Typical Dosage for Pitavastatin
Adult: 1 -2 mg /day
Schedule of Pitavastatin
Storage Requirements for Pitavastatin
Store at room temperature at a range of 15 to 25degree C. Protect from heat, light and moisture. Keep out of the reach of children.
Effects of Missed Dosage of Pitavastatin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Pitavastatin
Provide supportive measures and symptomatic treatment.

Home Delivery for Pitavastatin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including pitavastatin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for pitavastatin and other medicines and health products. Home delivery services for pitavastatin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take pitavastatin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for pitavastatin before they complete the sale. You can get this information while placing the order for pitavastatin with the pharmacy.

Pitavastatin is a generic medicine name and there are several brands available for it. Some of the brands for pitavastatin might be better known than pitavastatin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have pitavastatin in stock, you can ask for one of the branded alternatives for pitavastatin.