General anaesthesia: It is often administered during the induction of anaesthesia to relax muscles of the jaw, neck and airway and thereby facilitate laryngoscopy and endotracheal intubation. Following induction, continued muscle relaxation is required for many procedures to aid surgical exposure and to provide additional insurance of immobility.
Distribution- Widely distributed in the body as plasma protein bounded (77 to 91%) form.
Metabolism- Metabolized in the liver.
Excretion- Excreted through urine (unchanged form) and bile.
4. Increased blood pressure
5. Excessive salivation
6. Pain and burning at the injection site
2. Inability to control airway and/or support ventilations with oxygen and positive pressure
3. Neuromuscular diseases (e.g. Myasthenia gravis)
2. Myasthenia gravis
3. Renal impairment
4. Hepatic impairment
5. Pulmonary function impairment
6. Biliary tract disease
7. Severe obesity
2. Maintenance of muscle relaxation in patients undergoing mechanical ventilation
Azathioprine: Causes reversal of neuromuscular blocking effect of pancuronium.
Inhalation anaesthetics (Halothane, Enflurane, Isoflurane): Potentiation of neuromuscular blockade.
Magnesium Sulphate: Neuromuscular blockade of pancuronium enhanced.
Other neuromuscular blocking agents: (e.g. tubocuraine): Synergistic effect though the blockade is not prolonged.
Quinine: Effects of pancuronium enhanced.
Succinylcholine: Prior administration enhances the relaxant effect of pancuronium and its duration of action.
Theophylline: The effect of pancuronium may be reversed. Chances of cardiac arrhythmias.
0.1 mg/kg slow IV; repeat every 30-60 minutes as needed.
0.04 - 0.1 mg/kg slow IV push (newborn: 0.02 mg/kg )
Home Delivery for Pancuronium in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including pancuronium.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for pancuronium and other medicines and health products. Home delivery services for pancuronium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take pancuronium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for pancuronium before they complete the sale. You can get this information while placing the order for pancuronium with the pharmacy.
Pancuronium is a generic medicine name and there are several brands available for it. Some of the brands for pancuronium might be better known than pancuronium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have pancuronium in stock, you can ask for one of the branded alternatives for pancuronium.