Alprazolam + Sertraline Pharmacology
Alprazolam + Sertraline
Varies with weight and severity of the disease. Following Alprazolam combinations are available in the market. The dosage has to be decided by the treating specialist.
Each tablet contains
Alprazolam 0.25 mg + Sertraline 25 mg or
Alprazolam 0.5 mg + Sertraline 25 mg or
Alprazolam 0.5 mg + Sertraline 50 mg
Alprazolam
2.Drowsiness
3.Light headedness
4. Slurred speech
5.Nausea
6.Constipation or diarrhoea
7.Tremor
8.Dependence
9.Anorexia
0.Confusion
11.Light headedness
12.Mood changes
13.Muscle rigidity
14.Amnesia
2.Acute angle closure glaucoma
2.Hepatic impairment
3.Pulmonary insufficiency
4.Drug abuse
5.Bipolar disorder
6.Driving vehicles and operating machines and people involving any other dangerous activities
NEONATES- contraindicated
2.Treatment of Panic disorder.
Aminophylline: Antagonizes the sedative effect.
Cimetidine, Oral contraceptives, Disulfiram, Fluoxetine, Isoniazid, Ketoconazole, Metoprolol, Propoxyphene, Propranolol,
Valproic Acid: Elimination of alprazolam decreased due to inhibition of hepatic metabolism leading to enhanced activity.
Digoxin: Increase in serum concentration of Digoxin.
Imipramine & Desipramine: Enhanced activity of these drugs.
Levodopa: Decrease in antiparkinsonism efficacy.
Rifampicine: Decreases efficacy.
Anxiety: 0.25 - 0.5 mg every 8 hours in a day. Depending on the severity of the disease the dose can be gradually increased every 3 or 4 days.
Maximum dose: 4 mg / day in divided dose.
Anxiety with depression: 0.5 mg every 8 hours in a day
Maintenance dose: 1.5 - 4.5 mg/ day in divided dose
Panic disorder: starting dose: 1.5 mg /day in 3 divided dose. Depending on the severity of the disease the dose can be gradually increased every 3 or 4 days.
Children: Not recommended
Sertraline
Distribution: It is distributed in the body in protein bound form.
Metabolism: It undergoes hepatic metabolism and produces active metabolites.
Excretion: Excreted in urine and faeces.
2. Nausea
3. Diarrhoea
4. Headache
5. Fatigue
6. Dizziness
7. Tremor
8. Somnolence
9. Dry mouth
10. Anorexia
11. Impotence
12. Increased sweating
13. Constipation
14. Dyspepsia
15. Agitation
16. Malaise
17. Abdominal pain
2. Patient on MAOI (Monoamine oxidase inhibitor) therapy
2. Renal impairment
3. Epilepsy
4. Hypomania
5. Metabolic disorder
6. Alcoholics
7. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Sertraline is started)
8. Use cautiously in patient at risk for suicide
9. Use caution while driving vehicle, operating machine and activities requiring mental alertness or judgment
NEONATES: Contraindicated
2. Post traumatic stress disorder
3. Depression
4. Obsessive compulsive disorder
Lithium: On concomitant use, increased incidence of mild to moderate tremors has been observed.
Warfarin : Sertraline with warfarin may increase prothrombin time.
Panic disorder, Post traumatic stress disorder: Initial dose: 25 mg / day dose can be gradually increased every week if sufficient response does not occurs.
Maximum dose: 200 mg / day
Depression, Obsessive compulsive disorder: Initial dose: 50 mg / day dose can be gradually increased every week if sufficient response does not occur.
Maximum dose: 200 mg / day
Home Delivery for Alprazolam + Sertraline in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for alprazolam + sertraline and other medicines and health products. Home delivery services for alprazolam + sertraline may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take alprazolam + sertraline only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for alprazolam + sertraline before they complete the sale. You can get this information while placing the order for alprazolam + sertraline with the pharmacy.
Alprazolam + Sertraline is a generic medicine name and there are several brands available for it. Some of the brands for alprazolam + sertraline might be better known than alprazolam + sertraline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have alprazolam + sertraline in stock, you can ask for one of the branded alternatives for alprazolam + sertraline.
