Antiparkinsonian action: MAO-B (Monoamine oxidase enzyme-B) in the CNS is responsible for the metabolism of Dopamine to DOPAC (3, 4 Dihydroxy-phenyl acetic acid). Selegiline binds to MAO-B and inhibits the Dopamine degradation. Selegiline produces an increase in the concentration of Dopamine in the CNS and therefore used in the treatment of Parkinsonism.
Distribution: It is widely distributed in the body in protein bound form.
Metabolism: In the liver it is metabolised to active metabolites such as Amphetamine, Methamphetamine and N-Desmethyldeprenyl.
Excretion: It is excreted mainly through urine.
3. Abdominal pain
5. Abdominal pain
8. Dryness of mouth
12. Increased akinetic activity
13. Loss of balance
17. Angina pectoris
18. Weight loss
2. Patient on opiate therapy
2. Angina pectoris
4. Peptic ulcer
Analgesics: Hyperpyrexia and CNS toxicity with pethidine.
Antidepressants: Hypertension & CNS excitation with fluoxetine.
Home Delivery for Selegiline in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including selegiline.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for selegiline and other medicines and health products. Home delivery services for selegiline may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take selegiline only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for selegiline before they complete the sale. You can get this information while placing the order for selegiline with the pharmacy.
Selegiline is a generic medicine name and there are several brands available for it. Some of the brands for selegiline might be better known than selegiline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have selegiline in stock, you can ask for one of the branded alternatives for selegiline.