Escitalopram Pharmacology


About Escitalopram
Selective Serotonin Reuptake Inhibitor (SSRI), Antidepressant.
Mechanism of Action of Escitalopram
Escitalopram is the S enantiomer of racemic Citalopram. It is 100 times more potent than R-enantiomer. Escitalopram blocks the re-uptake of neurotransmitter Serotonin from the synapse to the presynaptic nerve terminal in the CNS. This potentiates the action of Serotonin (5HT) and it is useful in the treatment of depression.
Pharmacokinets of Escitalopram
Absorption: Escitalopram is well absorbed after oral administration. Distribution: It is widely distributed in the body. Metabolism: Escitalopram undergoes metabolism in the liver and the metabolites are not as active as Escitalopram. Excretion: It is excreted mainly through urine.
Onset of Action for Escitalopram
1 week
Duration of Action for Escitalopram
Half Life of Escitalopram
27 - 32 hours
Side Effects of Escitalopram
5.Dry mouth
7.Increased sweating
13.Abdominal pain
16.Ejaculation disorder
19.Upper respiratory tract infection
Contra-indications of Escitalopram
1. Hypersensitivity to Escitalopram or Citalopram
2. Patient on MAOI (Monoamine oxidase inhibitor) therapy.
Special Precautions while taking Escitalopram
1. Hepatic impairment
2. Renal impairment
3. Myocardial infarction
4. Cardiac failure
5. Epilepsy
6. Mania
7. Alcoholics
8. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Escitalopram is started)
9. Use cautiously in patient at risk for suicide
10. Use caution while driving vehicle, operating machine and activities requiring mental alertness or judgment
11. Withdraw the drug gradually with caution
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
NEONATES: contraindicated
Indications for Escitalopram
Interactions for Escitalopram
Typical Dosage for Escitalopram
Adult: Initial dose: 10 mg / day, dose can be increased to 20 mg / day if sufficient response does not occur after a minimum of 1 week.
Schedule of Escitalopram
Storage Requirements for Escitalopram
Store at 15 - 30 degree C. Keep out of the reach of children. Protect from heat and light.
Effects of Missed Dosage of Escitalopram
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose
Effects of Overdose of Escitalopram
Give supportive measures and treatment. Drug can be removed from the body by gastric lavage. Absorption of the drug can be reduced by the administration of Activated charcoal.

Home Delivery for Escitalopram in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including escitalopram.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for escitalopram and other medicines and health products. Home delivery services for escitalopram may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take escitalopram only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for escitalopram before they complete the sale. You can get this information while placing the order for escitalopram with the pharmacy.

Escitalopram is a generic medicine name and there are several brands available for it. Some of the brands for escitalopram might be better known than escitalopram itself. If the pharmacy that's willing to deliver medicines to your home doesn't have escitalopram in stock, you can ask for one of the branded alternatives for escitalopram.