Penfluridol Pharmacology


About Penfluridol
First generation diphenylbutylpiperidine, Antipsychotic.
Mechanism of Action of Penfluridol
Penfluridol binds to the dopamine receptor (D1, D2, D3 &D4).It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system and in mesocortical area. Peripherally and centrally it acts as a competitive Dopamine antagonist.
Pharmacokinets of Penfluridol
Absorption: It is absorbed after oral administration. Distribution: It is extensively distributed in fatty tissues. Metabolism: Penfluridol is metabolised in the liver. Excretion: It is excreted mainly in urine and also in faeces.
Onset of Action for Penfluridol
2 - 4 weeks.
Duration of Action for Penfluridol
Upto 7 days.
Half Life of Penfluridol
199 hour.
Side Effects of Penfluridol
2.Dry mouth
4.Blurred vision
5.Urine retention
7.Weight gain
8.Cholestatic jaundice
Contra-indications of Penfluridol
1.Hypersensitivity to Penfluridol
3.Bone marrow suppression
Special Precautions while taking Penfluridol
2.Debilitated patient

Pregnancy Related Information
Use with caution.
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution.
Children Related Information
NEONATES: Contraindicated
Indications for Penfluridol
Interactions for Penfluridol
Typical Dosage for Penfluridol
20 - 60 mg once weekly Dose can be gradually increased up to 250 mg / day
Schedule of Penfluridol
Storage Requirements for Penfluridol
The drug should be kept at 15-30 degree C in a tightly closed container. Protect from heat and light. Keep out of the reach of children
Effects of Missed Dosage of Penfluridol
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose
Effects of Overdose of Penfluridol
Give supportive measures and treatment.

Home Delivery for Penfluridol in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including penfluridol.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for penfluridol and other medicines and health products. Home delivery services for penfluridol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take penfluridol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for penfluridol before they complete the sale. You can get this information while placing the order for penfluridol with the pharmacy.

Penfluridol is a generic medicine name and there are several brands available for it. Some of the brands for penfluridol might be better known than penfluridol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have penfluridol in stock, you can ask for one of the branded alternatives for penfluridol.