Amphetamine Pharmacology

Amphetamine

About Amphetamine
Sympathomimetic agent, Phenethylamine derivative, Appetite suppressant, a psychostimulant.
Mechanism of Action of Amphetamine
Amphetamine is a sympathomimetic amine with CNS stimulant activity. It primarily acts in the cerebral cortex and reticuloendothelial system. Amphetamines block the reuptake of Norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extra neuronal space.It releases Norepinephrine and promotes nerve impulse transmission.At high doses effects are mediated by Dopamine.
Pharmacokinets of Amphetamine
Absorption:It is completely absorbed after oral administration.Distribution:It is distributed widely in the body.Metabolism:It is metabolized in the liver.Excretion:It is excreted in the urine.
Onset of Action for Amphetamine
N/A
Duration of Action for Amphetamine
4 - 24 hour
Half Life of Amphetamine
N/A
Side Effects of Amphetamine
1.Restlessness
2.Diarrhoea
3.Dry mouth
4.Constipation
5.Tachycardia
6.Palpitation
7.Insomnia
8.Hypertension
9.Tremor
10.Urticaria
11.Impotence
Contra-indications of Amphetamine
1.Hypersensitivity to Amphetamine
2.Cardiovascular disease
3.Hyperthyroidism
4.Hypertension
5.Glaucoma
6.Arteriosclerosis
7.Patient on MAO therapy
Special Precautions while taking Amphetamine
1.Hyperexcitable patients
2.Patient with suicidal tendencies
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
N/A
Children Related Information
Children: Below 12 years: Contraindicated
Indications for Amphetamine
1.Attention deficit disorder with hyperactivity
2.Narcolepsy
Interactions for Amphetamine
N/A
Typical Dosage for Amphetamine
Adult:
Attention deficit disorder with hyperactivity: 5mg/day, dose can be increased by 5mg every week up to 60mg/day until desired response is attained
Narcolepsy: 10mg/day, dose can be increased by 10mg every week upto 60mg/day until desired response is attained
Children:
Attention deficit disorder with hyperactivity:
Above 5 years: 5mg/day,dose can be increased by 5mg every week up to 40mg/day
3 - 5years: 2.5mg/day, dose can be increased by 2.5mg weekly until desired response is achieved
Narcolepsy:
Children above 12 years: 10mg/day and dose can be increased by 10mg weekly until sufficient response is achieved
Children 6 - 12 years: 5mg/day and dose can be increased by 5mg weekly until sufficient response is achieved
Schedule of Amphetamine
X
Storage Requirements for Amphetamine
Store at 15 - 30 degree C. Keep out of the reach of children
Effects of Missed Dosage of Amphetamine
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Amphetamine
Give supportive measures and symptomatic treatment. Gastric lavage can be done if the ingestion is recent. Haemodialysis or peritoneal dialysis can be done if needed.

Home Delivery for Amphetamine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including amphetamine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for amphetamine and other medicines and health products. Home delivery services for amphetamine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take amphetamine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for amphetamine before they complete the sale. You can get this information while placing the order for amphetamine with the pharmacy.

Amphetamine is a generic medicine name and there are several brands available for it. Some of the brands for amphetamine might be better known than amphetamine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amphetamine in stock, you can ask for one of the branded alternatives for amphetamine.