Codergocrine Pharmacology


About Codergocrine
Dihydrogenated ergot alkaloid derivative , Adrenergic alpha-Antagonists, Nootropic Agents; Vasodilator Agents
Mechanism of Action of Codergocrine
Dihydroergotoxine is a semi synthetic ergot alkaloid. It has alpha adrenolytic action. It activates the metabolism of brain cells and increases the cerebral blood flow. Dihydroergotoxine increases the releases of Acetylcholine from the cortical slices neurotransmitters. It also enhances the concentration of neurotransmitters Dopamine and Serotonin in certain areas of brain.
Pharmacokinets of Codergocrine
Absorption: Dihydroergotoxine is rapidly but incompletely absorbed after oral administration. Distribution: It is distributed in protein bound form. Metabolism: 50% of the drug undergoes first pass metabolism and rest undergoes hepatic metabolism.
Onset of Action for Codergocrine
2-3 months.
Duration of Action for Codergocrine
Half Life of Codergocrine
2.6 - 5.1 hours
Side Effects of Codergocrine
2.Epigastric distress
4.Nasal congestion
5.Orthostatic hypotension
Contra-indications of Codergocrine
1.Hypersensitivity to Dihydroergotoxine and other ergot preparations
Special Precautions while taking Codergocrine
1.Hepatic diseases
2.Severe Bradycardia
5.Acute intermittent Porphyria
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
NEONATES: contraindicated
Indications for Codergocrine
1.Dementia of Alzheimer type
2.Multi infarct dementia
3.Senile dementia
4.Primary progressive dementia
Interactions for Codergocrine
No known interactions.
Typical Dosage for Codergocrine
Adults: 3-6 mg daily in divided doses.
Children: Not recommended.
Schedule of Codergocrine
Storage Requirements for Codergocrine
Store at 15 - 30 degree C in a tightly closed container. Keep out of the reach of children.
Effects of Missed Dosage of Codergocrine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Codergocrine
Give supportive measures and symptomatic treatment.

Home Delivery for Codergocrine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including codergocrine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for codergocrine and other medicines and health products. Home delivery services for codergocrine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take codergocrine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for codergocrine before they complete the sale. You can get this information while placing the order for codergocrine with the pharmacy.

Codergocrine is a generic medicine name and there are several brands available for it. Some of the brands for codergocrine might be better known than codergocrine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have codergocrine in stock, you can ask for one of the branded alternatives for codergocrine.