Nicergoline Pharmacology


About Nicergoline
Ergot alkaloid(an ergoloid mesylate derivative), Antidementia, a cerebral vasodilator and in peripheral vascular disease.
Mechanism of Action of Nicergoline
Nicergoline has alpha adrenolytic action which activates blood flow to the brain, lowers vascular resistances, stimulates the use of glucose and oxygen in the brain, increases metabolism of brain cells and protect the brain from insufficient oxygen supply. Nicergoline slows the deposit of the age pigment Lipofuscin in the brain and prevents the free radical damage to brain cells. Nicergoline produces increased intelligence, memory, learning and recall.
Pharmacokinets of Nicergoline
Onset of Action for Nicergoline
Duration of Action for Nicergoline
Half Life of Nicergoline
Side Effects of Nicergoline
1. Gastrointestinal disturbances
2. Agitation
3. Hypotension
4. Dizziness
5. Hot flushes
6. Insomnia
Contra-indications of Nicergoline
1. Porphyria
Special Precautions while taking Nicergoline
1. Myocardial infarction
2. Hypertension
3. Bradycardia
4. Acute bleeding
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
NEONATES : Contraindicated
Indications for Nicergoline
1. Cerebral arteriosclerosis
2. Cerebral thrombosis
3. Cerebral embolism
4. Migraines of vascular origin
5. Retinal thrombosis
6. Dementia of Alzheimer type
7. Multi infarct dementia
Interactions for Nicergoline
May enhance the cardiac depressant action of propanolol.
Typical Dosage for Nicergoline
Adult: 15 - 30 / day in 3 divided doses
Dementia: 30 - 60 mg daily for 3 weeks
Schedule of Nicergoline
Storage Requirements for Nicergoline
Store at 15 - 30 degree C in a tightly closed container. Keep out of the reach of children.
Effects of Missed Dosage of Nicergoline
Take the missed dose as soon as noticed. If it is the time for next dose then skip the missed dose and take that dose. Do not double the dose.
Effects of Overdose of Nicergoline
Give supportive measures and symptomatic treatment. Treat hypotension with Noradrenaline or Angiotensin.

Home Delivery for Nicergoline in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including nicergoline.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for nicergoline and other medicines and health products. Home delivery services for nicergoline may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take nicergoline only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for nicergoline before they complete the sale. You can get this information while placing the order for nicergoline with the pharmacy.

Nicergoline is a generic medicine name and there are several brands available for it. Some of the brands for nicergoline might be better known than nicergoline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have nicergoline in stock, you can ask for one of the branded alternatives for nicergoline.