- Medicine India
- Generic Medicines
- Pharmacology For Rivastigmine
RivastigmineAbout RivastigmineA central reversible non competitive Anticholinesterase, Antidementia.Mechanism of Action of RivastigmineAlzheimer`s disease may result from a deficiency in neurotransmitters used by nerves in the brain to communicate with one another. Rivastigmine exerts its therapeutic effect by enhancing its cholinergic function. It increases the concentration of Acetylcholine through reversible inhibition of acetyl cholinesterase enzyme which is involved in the hydrolysis of Acetylcholine. It leads to increased concentration of Acetylcholine.This increased Acetylcholine concentrations are believed to be responsible for the improvement seen during treatment with Rivastigmine.Pharmacokinets of RivastigmineAbsorption: It is rapidly absorbed after oral administration and its bioavailability is about 40%. Distribution: Rivastigmine is widely distributed in the body in protein bound and unbound form. It crosses blood brain barrier
Metabolism: It is extensively metabolised in the liver. Excretion: Rivastigmine and its metabolites are excreted mainly in urine and very small amount in faeces.Onset of Action for RivastigmineN/ADuration of Action for Rivastigmine10 hoursHalf Life of Rivastigmine1.5 hoursSide Effects of Rivastigmine1. Nausea
8. Accidental trauma
13. Gastrointestinal haemorrhage
14. Frequent urination
15. Increased sweating
17. Urinary tract infection
Contra-indications of Rivastigmine1. Hypersensitivity to RivastigmineSpecial Precautions while taking Rivastigmine1. Hepatic impairment
2. Renal impairment
3. Cardiovascular diseases
4. Supraventricular cardiac conduction conditions like sick sinus syndrome
6. Chronic obstructive pulmonary diseases
7. Ulcers (gastric or duodenal)
8. Use caution while driving vehicles, operating machine or performing any hazardous activities.
Pregnancy Related InformationContraindicated
Old Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicated
NEONATES: ContraindicatedIndications for Rivastigmine1. Mild to moderate dementia of the Alzheimer`s type.Interactions for RivastigmineN/ATypical Dosage for RivastigmineAdult: 3mg / day in 2 divided doses with food dose can be increased by 3mg / day every 2 weeks.
Maximum dose: 12 mg / day
Schedule of RivastigmineN/AStorage Requirements for RivastigmineStore at 15 - 30 degree C in a tightly closed container. Protect from heat and light. Keep out of the reach of children.Effects of Missed Dosage of RivastigmineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the doseEffects of Overdose of RivastigmineGive supportive measures and symptomatic treatment. Atropine can be given as antidote.
Home Delivery for Rivastigmine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including rivastigmine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for rivastigmine and other medicines and health products. Home delivery services for rivastigmine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take rivastigmine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for rivastigmine before they complete the sale. You can get this information while placing the order for rivastigmine with the pharmacy.
Rivastigmine is a generic medicine name and there are several brands available for it. Some of the brands for rivastigmine might be better known than rivastigmine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have rivastigmine in stock, you can ask for one of the branded alternatives for rivastigmine.