Doxylamine Succinate Pharmacology

Doxylamine Succinate

About Doxylamine Succinate

First Generation H1 Antagonist, Ethanolamine Derivative, Antiemetic, Antihistamine.

Mechanism of Action of Doxylamine Succinate

Doxylamine succinate is an ethanolamine derivative. It blocks the effect of Histamine and also induces sedation. It has anticholinergic and Antiemetic properties also.

Pharmacokinets of Doxylamine Succinate

Absorption: Doxylamine succinate is absorbed after oral administration. Metabolism: It undergoes metabolism in the liver. Excretion: It is excreted mainly in urine

Onset of Action for Doxylamine Succinate

N/A

Duration of Action for Doxylamine Succinate

N/A

Half Life of Doxylamine Succinate

10 hours

Side Effects of Doxylamine Succinate

1.Drowsiness
2.Dry mouth
3.Blurred vision
4.Dizziness
5.Urinary retention
6.Abdominal discomfort

Contra-indications of Doxylamine Succinate

1.Asthma
2.Glaucoma
3.Prostatic hypertrophy
4.Hypersensitivity to Doxylamine succinate

Special Precautions while taking Doxylamine Succinate

1.Narrow angle glaucoma
2.Pyloroduodenal obstruction
3.Epilepsy
4.Urinary retention
5.Cardiac failure
6.Hypertension
7.Avoid alcohol
8.Patient should be cautioned about driving vehicle or operating machines

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution
CHILDREN below 12 year: contraindicated

Indications for Doxylamine Succinate

1.Nausea and vomiting in pregnancy
2.Insomnia

Interactions for Doxylamine Succinate

Alcohol, MAOIs & CNS depressants: CNS depressant effect enhanced.
Atropine and TCAs: Additive anti-muscarinic effect.

Typical Dosage for Doxylamine Succinate

Adult:
Insomnia: 25 mg to be taken half an hour before going to bed.

Schedule of Doxylamine Succinate

Storage Requirements for Doxylamine Succinate

Store the drug at 15 - 30 degree C in tightly closed container. Protect from heat and light.

Effects of Missed Dosage of Doxylamine Succinate

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Doxylamine Succinate

Give supportive measures and symptomatic treatment.

Home Delivery for Doxylamine Succinate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including doxylamine succinate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for doxylamine succinate and other medicines and health products. Home delivery services for doxylamine succinate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take doxylamine succinate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for doxylamine succinate before they complete the sale. You can get this information while placing the order for doxylamine succinate with the pharmacy.

Doxylamine Succinate is a generic medicine name and there are several brands available for it. Some of the brands for doxylamine succinate might be better known than doxylamine succinate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have doxylamine succinate in stock, you can ask for one of the branded alternatives for doxylamine succinate.