Pregabalin Pharmacology

Pregabalin

About Pregabalin
A GABA agonist, Anticonvulsant.
Mechanism of Action of Pregabalin
Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.
Pharmacokinets of Pregabalin
Absorption: Pregabalin is rapidly absorbed after oral doses.Pregabalin is not bound to plasma proteins and undergoes negligible metabolism.Excretion: It is excreted mainly in urine.
Onset of Action for Pregabalin
N/A
Duration of Action for Pregabalin
N/A
Half Life of Pregabalin
6-7 hours
Side Effects of Pregabalin
1.Dizziness
2.Somnolence
3.Blurred vision
4.Diplopia
5.Increased appetite
6.Weight gain
7.Dry mouth
8.Constipation
9.Vomiting
10.Flatulence
11.Euphoria
12.Confusion
13.Reduced libido
14.Erectile dysfunction
15.Irritability
16.Vertigo
17.Ataxia
18.Tremor
19.Dysarthria
20.Paraesthesia
21.Fatigue
22.Oedema
23.Disturbances of attention, memory, coordination, and gait also occur frequently
Contra-indications of Pregabalin
1.Hypersensitivity to Pregabalin
Special Precautions while taking Pregabalin
1.Renal impairment
2.Driving vehicles, operating machines and people involving any other dangerous activities
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
N/A
Indications for Pregabalin
1.Epilepsy
2.Generalised anxiety disorder
3.Neuropathic pain
Interactions for Pregabalin
N/A
Typical Dosage for Pregabalin
150- 300mg / day in 2 divided doses
Schedule of Pregabalin
N/A
Storage Requirements for Pregabalin
Store it at 15 -25 degree C in a tightly closed container .Protect away from heat and light. Keep out of the reach of children.
Effects of Missed Dosage of Pregabalin
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose and do not double the dose
Effects of Overdose of Pregabalin
Give supportive measures and symptomatic treatment.

Home Delivery for Pregabalin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including pregabalin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for pregabalin and other medicines and health products. Home delivery services for pregabalin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take pregabalin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for pregabalin before they complete the sale. You can get this information while placing the order for pregabalin with the pharmacy.

Pregabalin is a generic medicine name and there are several brands available for it. Some of the brands for pregabalin might be better known than pregabalin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have pregabalin in stock, you can ask for one of the branded alternatives for pregabalin.