Betahistine Pharmacology

Betahistine

About Betahistine
H1 selective histamine analogue, diamine oxidase inhibitor, anti vertigo and in Meniere?s syndrome.
Mechanism of Action of Betahistine
Betahistine is a histamine substitute. It produces vasodilatation and improves blood flow to the labyrinth and brain stem. There by it reduces the frequency of episodes of vertigo in patient with Meniere`s syndrome.
It works directly on histamine receptors. These receptors are found in blood vessel walls including those in the ear. Activation of these receptors will results in the widening of blood vessels. This improves circulation reducing the pressure in the ear. Its main use is in treating Meniere`s disease. It helps in relieving the inner ear pressure and by reducing the frequency and severity of nausea and vertigo attacks. It also reduces tinnitus thus helping to restore normal hearing.
.
Pharmacokinets of Betahistine
Absorption: It is very rapidly absorbed after oral administration. Metabolism: Betahistine is rapidly metabolised in the liver to 2-pyridylacetic acid. Excretion: Excreted mainly in urine
Onset of Action for Betahistine
Within 1 hr.
Duration of Action for Betahistine
6-12 hours.
Half Life of Betahistine
3.5 hours
Side Effects of Betahistine
1.Headache
2.Rashes
3.Pruritis
4.Gastrointestinal disturbances
5.Nausea
6.Urticaria
7.Dizziness
8.Insomnia
9.Dyspepsia
Contra-indications of Betahistine
1.Hypersensitivity to Betahistine
2.Pheochromocytoma
Special Precautions while taking Betahistine
1.Asthma
2.Ulcer
3.Patient receiving antihistamines
Pregnancy Related Information
Use with caution.
Old Age Related Information
Use with caution.
Breast Feeding Related Information
Use with caution.
Children Related Information
Contraindicated
Indications for Betahistine
1.Meniere`s syndrome
2.Vertigo

Interactions for Betahistine
Antihistaminics : Betahistine dihydrochloride antagonises the effects of antihistaminics
Typical Dosage for Betahistine
Adult: 8 mg 3 times daily with meals. Dose can be increased if needed to 48 mg / day.
Children: not recommended
Schedule of Betahistine
H
Storage Requirements for Betahistine
Store at room temperature. Protect from light and moisture.
Effects of Missed Dosage of Betahistine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betahistine
Give supportive measures and symptomatic treatment.

Home Delivery for Betahistine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including betahistine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for betahistine and other medicines and health products. Home delivery services for betahistine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take betahistine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for betahistine before they complete the sale. You can get this information while placing the order for betahistine with the pharmacy.

Betahistine is a generic medicine name and there are several brands available for it. Some of the brands for betahistine might be better known than betahistine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have betahistine in stock, you can ask for one of the branded alternatives for betahistine.