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- Pharmacology For Chlorpheniramine Maleate + Phenylpropanolamine
Chlorpheniramine Maleate + Phenylpropanolamine Pharmacology
Chlorpheniramine Maleate + PhenylpropanolamineAbout Chlorpheniramine Maleate + PhenylpropanolamineN/AMechanism of Action of Chlorpheniramine Maleate + PhenylpropanolamineN/APharmacokinets of Chlorpheniramine Maleate + PhenylpropanolamineN/AOnset of Action for Chlorpheniramine Maleate + PhenylpropanolamineN/ADuration of Action for Chlorpheniramine Maleate + PhenylpropanolamineN/AHalf Life of Chlorpheniramine Maleate + PhenylpropanolamineN/ASide Effects of Chlorpheniramine Maleate + PhenylpropanolamineN/AContra-indications of Chlorpheniramine Maleate + PhenylpropanolamineN/ASpecial Precautions while taking Chlorpheniramine Maleate + PhenylpropanolamineN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Chlorpheniramine Maleate is contraindicated in breast feeding the combination generic cannot be used in breast feeding mother.Children Related InformationN/AIndications for Chlorpheniramine Maleate + PhenylpropanolamineCoughInteractions for Chlorpheniramine Maleate + PhenylpropanolamineN/ATypical Dosage for Chlorpheniramine Maleate + PhenylpropanolamineAdult: 1 tablet to be taken 2 times daily or as directed by the PhysicianSchedule of Chlorpheniramine Maleate + PhenylpropanolamineN/AStorage Requirements for Chlorpheniramine Maleate + PhenylpropanolamineN/AEffects of Missed Dosage of Chlorpheniramine Maleate + PhenylpropanolamineN/AEffects of Overdose of Chlorpheniramine Maleate + PhenylpropanolamineN/A
Chlorpheniramine MaleateAbout Chlorpheniramine MaleateN/AMechanism of Action of Chlorpheniramine MaleateN/APharmacokinets of Chlorpheniramine MaleateN/AOnset of Action for Chlorpheniramine MaleateN/ADuration of Action for Chlorpheniramine MaleateN/AHalf Life of Chlorpheniramine MaleateN/ASide Effects of Chlorpheniramine MaleateN/AContra-indications of Chlorpheniramine MaleateFirst Generation alkylamine H1 Antagonist, Antihistamine.Special Precautions while taking Chlorpheniramine MaleateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Chlorpheniramine MaleateN/AInteractions for Chlorpheniramine MaleateN/ATypical Dosage for Chlorpheniramine MaleateN/ASchedule of Chlorpheniramine MaleateN/AStorage Requirements for Chlorpheniramine MaleateN/AEffects of Missed Dosage of Chlorpheniramine MaleateN/AEffects of Overdose of Chlorpheniramine MaleateN/A
PhenylpropanolamineAbout PhenylpropanolamineAlfa-and Beta-adrenergic agonist, Phenethylamine derivative, a stimulant, decongestant,anorectic.Mechanism of Action of PhenylpropanolamineIt is a mixed acting sympathomimetic amine with predominant alpha adrenergic agonistic action. It exerts nasal decongestant action by acting through alpha adrenergic receptors in the respiratory tract mucosa; and produces vasoconstriction. It temporarily reduces the swelling associated with inflammation of nasal mucosa.
Phenylpropanolamine also suppresses the appetite control center in the hypothalamus
Pharmacokinets of PhenylpropanolamineAbsorption: Well absorbed orally, Metabolism: Metabolized in to an active metabolite in liver, Excretion: Excreted mainly through urine.Onset of Action for Phenylpropanolamine15 to 30 minutesDuration of Action for Phenylpropanolamine3 hoursHalf Life of PhenylpropanolamineN/ASide Effects of Phenylpropanolamine1. Hypertension
4. Renal failure
6. Psychotic disturbances
8. SeizuresContra-indications of Phenylpropanolamine1. Hypersensitivity to Phenylpropanolamine or other sympathomimetics
2. Coronary artery disease
6. Angle-closure glaucoma
8. Renal impairment
10. During or within 14 days of use of MAO inhibitors
11. Use as an anorexiant for children less than 12 years of age
12. Sustained-release forms during lactation and in children less than 12 years of age
Special Precautions while taking Phenylpropanolamine1. Cardiovascular disorders
2. Mild Hypertension
3. Prostatic hypertrophy
4. Psychosis or other psychiatric disorders (Phenylpropanolamine may precipitate psychiatric disorders)
5. Not drinking large amounts of caffeine-containing beverages, such as coffee, tea, or colas
6. Do not engage in driving, using machines, or doing anything else that requires mental alertness while taking medication
7. Inform the physician if cold symptoms do not improve within 7 days or if fever is present
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Phenylpropanolamine1. Nasal congestion
Interactions for PhenylpropanolamineN/ATypical Dosage for PhenylpropanolamineOral:
As decongestant: 25mg every four hours or 50mg every 8 hours daily. Not to exceed 150mg/day
Anorexiant: 25mg thrice daily; 30minutes before meals.
Extended release tablets or capsules:As decongestant: 75mg twice daily
Anorexiant: 75mg once daily in the morning.
Children (6 to 12 years): 12.5mg up to every four hours. Not to exceed 75mg/day
Children (2 to 6years): 6.25mg up to every four hours. Not to exceed 37.5mg/day
Schedule of PhenylpropanolamineHStorage Requirements for PhenylpropanolamineStore at controlled room temperature at range of 15 to 30 degree C.; in a well closed container. Protect from light.Effects of Missed Dosage of PhenylpropanolamineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of PhenylpropanolamineProvide symptomatic treatment and supportive measures.Remove drug from the body by induced emesis or gastric lavage. Barbiturate sedatives are sometimes used to control excessive CNS stimulation. Monitor Cardiovascular and respiratory functions. Administer intravenous fluids to control hypotension. Correct hypertension with Intravenous phentolamine or nitrates. Perform forced diuresis by acidification of urine.
Home Delivery for Chlorpheniramine Maleate + Phenylpropanolamine in Your City
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Please be aware that you should take chlorpheniramine maleate + phenylpropanolamine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for chlorpheniramine maleate + phenylpropanolamine before they complete the sale. You can get this information while placing the order for chlorpheniramine maleate + phenylpropanolamine with the pharmacy.
Chlorpheniramine Maleate + Phenylpropanolamine is a generic medicine name and there are several brands available for it. Some of the brands for chlorpheniramine maleate + phenylpropanolamine might be better known than chlorpheniramine maleate + phenylpropanolamine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chlorpheniramine maleate + phenylpropanolamine in stock, you can ask for one of the branded alternatives for chlorpheniramine maleate + phenylpropanolamine.