Chlorpheniramine Maleate + Phenylpropanolamine Pharmacology

Chlorpheniramine Maleate + Phenylpropanolamine

About Chlorpheniramine Maleate + Phenylpropanolamine
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Mechanism of Action of Chlorpheniramine Maleate + Phenylpropanolamine
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Pharmacokinets of Chlorpheniramine Maleate + Phenylpropanolamine
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Onset of Action for Chlorpheniramine Maleate + Phenylpropanolamine
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Duration of Action for Chlorpheniramine Maleate + Phenylpropanolamine
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Half Life of Chlorpheniramine Maleate + Phenylpropanolamine
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Side Effects of Chlorpheniramine Maleate + Phenylpropanolamine
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Contra-indications of Chlorpheniramine Maleate + Phenylpropanolamine
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Special Precautions while taking Chlorpheniramine Maleate + Phenylpropanolamine
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Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated; since Chlorpheniramine Maleate is contraindicated in breast feeding the combination generic cannot be used in breast feeding mother.
Children Related Information
N/A
Indications for Chlorpheniramine Maleate + Phenylpropanolamine
Cough
Interactions for Chlorpheniramine Maleate + Phenylpropanolamine
N/A
Typical Dosage for Chlorpheniramine Maleate + Phenylpropanolamine
Adult: 1 tablet to be taken 2 times daily or as directed by the Physician
Schedule of Chlorpheniramine Maleate + Phenylpropanolamine
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Storage Requirements for Chlorpheniramine Maleate + Phenylpropanolamine
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Effects of Missed Dosage of Chlorpheniramine Maleate + Phenylpropanolamine
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Effects of Overdose of Chlorpheniramine Maleate + Phenylpropanolamine
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Chlorpheniramine Maleate

About Chlorpheniramine Maleate
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Mechanism of Action of Chlorpheniramine Maleate
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Pharmacokinets of Chlorpheniramine Maleate
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Onset of Action for Chlorpheniramine Maleate
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Duration of Action for Chlorpheniramine Maleate
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Half Life of Chlorpheniramine Maleate
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Side Effects of Chlorpheniramine Maleate
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Contra-indications of Chlorpheniramine Maleate
First Generation alkylamine H1 Antagonist, Antihistamine.
Special Precautions while taking Chlorpheniramine Maleate
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Chlorpheniramine Maleate
N/A
Interactions for Chlorpheniramine Maleate
N/A
Typical Dosage for Chlorpheniramine Maleate
N/A
Schedule of Chlorpheniramine Maleate
N/A
Storage Requirements for Chlorpheniramine Maleate
N/A
Effects of Missed Dosage of Chlorpheniramine Maleate
N/A
Effects of Overdose of Chlorpheniramine Maleate
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Phenylpropanolamine

About Phenylpropanolamine
Alfa-and Beta-adrenergic agonist, Phenethylamine derivative, a stimulant, decongestant,anorectic.
Mechanism of Action of Phenylpropanolamine
It is a mixed acting sympathomimetic amine with predominant alpha adrenergic agonistic action. It exerts nasal decongestant action by acting through alpha adrenergic receptors in the respiratory tract mucosa; and produces vasoconstriction. It temporarily reduces the swelling associated with inflammation of nasal mucosa.
Phenylpropanolamine also suppresses the appetite control center in the hypothalamus

Pharmacokinets of Phenylpropanolamine
Absorption: Well absorbed orally, Metabolism: Metabolized in to an active metabolite in liver, Excretion: Excreted mainly through urine.
Onset of Action for Phenylpropanolamine
15 to 30 minutes
Duration of Action for Phenylpropanolamine
3 hours
Half Life of Phenylpropanolamine
N/A
Side Effects of Phenylpropanolamine
1. Hypertension
2. Stroke
3. Arrhythmias
4. Renal failure
5. Rhabdomyolysis
6. Psychotic disturbances
7. Hallucinations
8. Seizures
Contra-indications of Phenylpropanolamine
1. Hypersensitivity to Phenylpropanolamine or other sympathomimetics
2. Coronary artery disease
3. Hypertension
4. Arteriosclerosis
5. Depression
6. Angle-closure glaucoma
7. Diabetes
8. Renal impairment
9. Hyperthyroidism
10. During or within 14 days of use of MAO inhibitors
11. Use as an anorexiant for children less than 12 years of age
12. Sustained-release forms during lactation and in children less than 12 years of age
Special Precautions while taking Phenylpropanolamine
1. Cardiovascular disorders
2. Mild Hypertension
3. Prostatic hypertrophy
4. Psychosis or other psychiatric disorders (Phenylpropanolamine may precipitate psychiatric disorders)
5. Not drinking large amounts of caffeine-containing beverages, such as coffee, tea, or colas
6. Do not engage in driving, using machines, or doing anything else that requires mental alertness while taking medication
7. Inform the physician if cold symptoms do not improve within 7 days or if fever is present
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Phenylpropanolamine
1. Nasal congestion

Interactions for Phenylpropanolamine
N/A
Typical Dosage for Phenylpropanolamine
Oral:
Adults:
As decongestant: 25mg every four hours or 50mg every 8 hours daily. Not to exceed 150mg/day
Anorexiant: 25mg thrice daily; 30minutes before meals.
Extended release tablets or capsules:As decongestant: 75mg twice daily
Anorexiant: 75mg once daily in the morning.
As decongestant:
Children (6 to 12 years): 12.5mg up to every four hours. Not to exceed 75mg/day
Children (2 to 6years): 6.25mg up to every four hours. Not to exceed 37.5mg/day

Schedule of Phenylpropanolamine
H
Storage Requirements for Phenylpropanolamine
Store at controlled room temperature at range of 15 to 30 degree C.; in a well closed container. Protect from light.
Effects of Missed Dosage of Phenylpropanolamine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Phenylpropanolamine
Provide symptomatic treatment and supportive measures.Remove drug from the body by induced emesis or gastric lavage. Barbiturate sedatives are sometimes used to control excessive CNS stimulation. Monitor Cardiovascular and respiratory functions. Administer intravenous fluids to control hypotension. Correct hypertension with Intravenous phentolamine or nitrates. Perform forced diuresis by acidification of urine.

Home Delivery for Chlorpheniramine Maleate + Phenylpropanolamine in Your City

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Please be aware that you should take chlorpheniramine maleate + phenylpropanolamine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for chlorpheniramine maleate + phenylpropanolamine before they complete the sale. You can get this information while placing the order for chlorpheniramine maleate + phenylpropanolamine with the pharmacy.

Chlorpheniramine Maleate + Phenylpropanolamine is a generic medicine name and there are several brands available for it. Some of the brands for chlorpheniramine maleate + phenylpropanolamine might be better known than chlorpheniramine maleate + phenylpropanolamine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chlorpheniramine maleate + phenylpropanolamine in stock, you can ask for one of the branded alternatives for chlorpheniramine maleate + phenylpropanolamine.