Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine Pharmacology

Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine

About Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
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Mechanism of Action of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
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Pharmacokinets of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
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Onset of Action for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Duration of Action for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Half Life of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
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Side Effects of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Contra-indications of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Special Precautions while taking Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Pregnancy Related Information
Contraindicated; since Dextromethrorphan and Chlorpheniramine maleate are contraindicated in pregnancy the combination generic cannot be used in pregnancy.
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated
Children Related Information
N/A
Indications for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
1.Cough
2. Nasal congestion
3.Rhinitis
4.Sneezing
Interactions for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Typical Dosage for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
Oral:
Adult: 10 ml to be taken 4 - 6 times daily
Children:
2-6 years: 2.5 - 5 ml to be taken 2 times daily
6-12 years: 5- 10ml to be taken 4 times daily
Schedule of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Storage Requirements for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Effects of Missed Dosage of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
N/A
Effects of Overdose of Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine
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Dextromethorphan

About Dextromethorphan
A synthetic morphine (((dextrorotatory methyl ether of Levorphanol))) derivative,A synthetic narcotic antitussive.
Mechanism of Action of Dextromethorphan
Dextromethorphan hydrobromide is a selective antitussive which raises threshold of cough centre and suppresses the cough reflex by direct action on the cough centre in the medulla. It does not depress mucociliary function of the airway mucosa and is also devoid of constipating and addicting actions. (((Its antitussive action is not exerted through opioid receptors)))
Pharmacokinets of Dextromethorphan
Absorption: Well absorbed orally, Metabolism: Extensively metabolized by liver, Excretion: Excreted primarily through urine as metabolites; about 7 to 10% is excreted through faeces.
Onset of Action for Dextromethorphan
Below ? an hour
Duration of Action for Dextromethorphan
3 to 6 hours
Half Life of Dextromethorphan
11 hours
Side Effects of Dextromethorphan
1. Dizziness
2. Nausea
3. Vomiting
4. Stomach pain
5. Drowsiness
6. Ataxia.
Contra-indications of Dextromethorphan
Patients currently taking MAO inhibitors or within two weeks of discontinuing MAO inhibitors.
Special Precautions while taking Dextromethorphan
1. Atopic children
2. Sedated or deliberate patients
3. Those patients confined to the supine position
4. Patients sensitive to aspirin
Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
May be used
Children below 2 years: Syrup, tablets, or lozenges are contraindicated
Indications for Dextromethorphan
Chronic nonproductive cough.
Interactions for Dextromethorphan
N/A
Typical Dosage for Dextromethorphan
Oral:
Chronic nonproductive cough:
Adults and children above 12 years: 10 to 20mg every 4 hours; or 30mg three to four times daily.
Maximum dose: 120mg daily.
Children (((age 6 to 12))): 5 to 10mg every four hours
Maximum dose: 60mg daily
Children (((age 2 to 6))): 2.5 to 5mg every four hours.
Maximum dose: 30mg daily.
Schedule of Dextromethorphan
N/A
Storage Requirements for Dextromethorphan
Store at room temperature in a well closed light resistant container. Protect from excess heat and moisture. Keep out of reach of children.
Effects of Missed Dosage of Dextromethorphan
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Dextromethorphan
Remove drug from the body by administration of activated charcoal and provide symptomatic treatment and supportive measures.

Chlorpheniramine Maleate

About Chlorpheniramine Maleate
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Mechanism of Action of Chlorpheniramine Maleate
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Pharmacokinets of Chlorpheniramine Maleate
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Onset of Action for Chlorpheniramine Maleate
N/A
Duration of Action for Chlorpheniramine Maleate
N/A
Half Life of Chlorpheniramine Maleate
N/A
Side Effects of Chlorpheniramine Maleate
N/A
Contra-indications of Chlorpheniramine Maleate
First Generation alkylamine H1 Antagonist, Antihistamine.
Special Precautions while taking Chlorpheniramine Maleate
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Chlorpheniramine Maleate
N/A
Interactions for Chlorpheniramine Maleate
N/A
Typical Dosage for Chlorpheniramine Maleate
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Schedule of Chlorpheniramine Maleate
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Storage Requirements for Chlorpheniramine Maleate
N/A
Effects of Missed Dosage of Chlorpheniramine Maleate
N/A
Effects of Overdose of Chlorpheniramine Maleate
N/A

Pseudoephedrine

About Pseudoephedrine
Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.
Mechanism of Action of Pseudoephedrine
It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.
Pharmacokinets of Pseudoephedrine
Absorption: Well absorbed orally, Distribution: Widely distributed throughout the body, Metabolism: Partially metabolized in liver by N-demethylation, Excretion: Excreted through urine mainly as unchanged drug and also as metabolites.
Onset of Action for Pseudoephedrine
30 minutes
Duration of Action for Pseudoephedrine
4 to 8 hours
Half Life of Pseudoephedrine
N/A
Side Effects of Pseudoephedrine
1. Rise in blood pressure
2. Tachycardia
3. Arrhythmias
4. CNS stimulation
5. Restlessness
6. Insomnia
7. Anxiety
8. Tremors
9. Skin rashes
10. Urinary retention
11. Respiratory difficulties
Contra-indications of Pseudoephedrine
1. Hypersensitivity to the drug
2. Severe hypertension
3. Coronary artery disease
4. Patients taking monoamine oxidase inhibitors (MAOIs) or who have taken MAOIs within the previous 14 days
5. Extended release preparations are contraindicated in children below 12 years
Special Precautions while taking Pseudoephedrine
1. Hypertension
2. Cardiac diseases
3. Diabetes
4. Glaucoma
5. Prostatic hyperplasia
6. Hyperthyroidism

Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Pseudoephedrine
1. Nasal and Eustachian tube congestion
2.Upper respiratory tract congestion
3.Adjunctive therapy in symptomatic relief of common cold, allergic rhinitis, blocked Eustachian tube, and upper respiratory tract infections
Interactions for Pseudoephedrine
N/A
Typical Dosage for Pseudoephedrine
Oral:
Adults and children over 12 years: 60mg 3 to 4 times daily
Maximum dose: 240mg/day
Children (age 6 to 12): 30mg 3 to 4 times daily
Maximum dose: 120mg/day
Children (age 2 to 6): 15mg 3 to 4 times daily
Maximum dose: 60mg/day or 4mg/kg.

Schedule of Pseudoephedrine
N/A
Storage Requirements for Pseudoephedrine
Store at controlled room temperature at a range of 15 to 30 degree C. Keep out of reach of children
Effects of Missed Dosage of Pseudoephedrine
Take the missed dose as soon as noticed and if it is the time for next dose
Effects of Overdose of Pseudoephedrine
Continue the regular schedule. Do not double the dose.
Over dosage and poisoning: Provide symptomatic treatment and supportive measures. Perform emesis and gastric lavage within 4 hours of ingestion. If renal function is adequate forced diuresis will increase elimination of the drug. (Do not force diuresis in severe poisoning). Monitor and assist vital signs, cardiac state and electrolyte balance. Treat cardiac toxicity with Propranolol or other effective drugs. Treat seizures with Diazepam (I.V.) and give dilute Potassium chloride solution for hypokalaemia.

Home Delivery for Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine in Your City

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Dextromethorphan + Chlorpheniramine maleate + Pseudoephedrine is a generic medicine name and there are several brands available for it. Some of the brands for dextromethorphan + chlorpheniramine maleate + pseudoephedrine might be better known than dextromethorphan + chlorpheniramine maleate + pseudoephedrine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextromethorphan + chlorpheniramine maleate + pseudoephedrine in stock, you can ask for one of the branded alternatives for dextromethorphan + chlorpheniramine maleate + pseudoephedrine.