Potassium chloride Injection Pharmacology

Potassium chloride Injection

About Potassium chloride Injection
Mechanism of Action of Potassium chloride Injection
Potassium is required for maintaining intracellular tonicity, maintaining balance between sodium across cell membranes, transmitting nerve impulses, maintaining cellular metabolism, contraction of cardiac, skeletal and smooth muscles, maintaining acid base balance and normal renal function.
Pharmacokinets of Potassium chloride Injection
Absorption: Well absorbed parenterally
Onset of Action for Potassium chloride Injection
Duration of Action for Potassium chloride Injection
Half Life of Potassium chloride Injection
Side Effects of Potassium chloride Injection
1. Nausea
2. Vomiting
3. Abdominal pain
4. Diarrhoea
5. Flatulence
6. Weakness or heaviness in legs
7. ECG changes
8. Arrythmias
9. Hyperklemia
10. Bleeding ulceration
11. Respiratory paralysis
Contra-indications of Potassium chloride Injection
1. Severe renal impairment with oliguria, anuria, or azotemia
2. In patients with untreated Addison`s disease
3. In acute dehydration
4. Heat cramps
5. Hyperkalemia from any cause
6. Patients receiving potassium sparing diuretics or aldosterone inhibiting agents
7. Conditions associated with extensive tissue break down.
Special Precautions while taking Potassium chloride Injection
1.Potassium replacement should be carried out only with ECG monitoring and frequent serum potassium determinations
2.Monitor serum electrolyte levels
3.Cardiac diseases
4.Renal diseases
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Potassium chloride Injection
1. Prevention and treatment of potassium depletion
Interactions for Potassium chloride Injection
Typical Dosage for Potassium chloride Injection
Adult: 10 - 20mEq / hr to be given as slow IV infusion
Schedule of Potassium chloride Injection
Storage Requirements for Potassium chloride Injection
Store in a cool dry place in a well closed container
Effects of Missed Dosage of Potassium chloride Injection
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Potassium chloride Injection
Gastric lavage is done if required. If potassium level is greater than 6.5mEq/L give treatment with continuous ECG monitoring. Infuse 40 to 160mEq. Sodium bicarbonate I.V. over a 5 minute interval and repeat in 10 to 15minutes if ECG abnormalities persist. Infuse 300 to 500ml of dextrose 10% to 25% over 1 hour. Insulin should be added to the infusion or administered as a separate injection. Patients with absent P waves or broad QRS complex who aren`t receiving cardiotonic glycosides should immediately be given 0.5 to 1g of calcium gluconate or another calcium salt I.V. over a 2 minute period with ECG monitoring to antagonize cardiotoxic effects of potassium. May be repeated in 1 to 2 minutes if ECG abnormalities persist. To remove potassium from the body use potassium polystyrene sulfonate resin, hemodialysis, or peritoneal dialysis. Administer potassium free I.V. fluids to correct water loss.

Home Delivery for Potassium chloride Injection in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for potassium chloride injection and other medicines and health products. Home delivery services for potassium chloride injection may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take potassium chloride injection only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for potassium chloride injection before they complete the sale. You can get this information while placing the order for potassium chloride injection with the pharmacy.

Potassium chloride Injection is a generic medicine name and there are several brands available for it. Some of the brands for potassium chloride injection might be better known than potassium chloride injection itself. If the pharmacy that's willing to deliver medicines to your home doesn't have potassium chloride injection in stock, you can ask for one of the branded alternatives for potassium chloride injection.