Beclomethasone Inhalers Pharmacology

Beclomethasone Inhalers

About Beclomethasone Inhalers
Potent glucocorticoid, Anti-inflammatory ,Anti asthmatic.
Mechanism of Action of Beclomethasone Inhalers
The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gamma interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells.
5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Beclomethasone Inhalers
Absorption- Poorly absorbed after inhalation from the lungs into systemic circulation
Elimination- It is eliminated through urine and feces
Onset of Action for Beclomethasone Inhalers
Duration of Action for Beclomethasone Inhalers
Half Life of Beclomethasone Inhalers
Side Effects of Beclomethasone Inhalers
1. Difficulty breathing.
2. Closing of the throat.
3. Swelling of the lips, tongue, or face.
4. Numbness.
5. Tingling.
6. Rash.
7. Worsening respiratory symptoms.
8. Dry mouth, nose, or throat after use.
9. Yeast (or other) infections in the mouth or throat.
10. Hoarseness or deepening of the voice, cough.
11. Sore throat.
12. Wheezing.
13. Glaucoma.
14. Headache.
15. Lightheadedness.
16. Unpleasant (or loss of) taste or smell.
17. Decreased growth in children taking large doses.
18. Cataracts
Contra-indications of Beclomethasone Inhalers
Hypersensitivity to the drug or any ingredients of it.
Special Precautions while taking Beclomethasone Inhalers
Pulmonary tuberculosis.
Pregnancy Related Information
Use with caution.
Old Age Related Information
Use with caution.
Breast Feeding Related Information
Use with caution.
Children Related Information
Use with caution.
Indications for Beclomethasone Inhalers
Prophylactic management of asthma.
Interactions for Beclomethasone Inhalers
There are no known drug interactions with Betamethasone inhalers
Typical Dosage for Beclomethasone Inhalers
Mild asthma- 50-100micrograms two times daily
Moderate asthma- 100-200micrograms two times daily
Severe asthma- 200-400micrograms two times daily
Children 6 to 12 years of age-
1 or 2 (42-100mcg) inhalations 3 or 4 times a day
Four inhalations (168-200) twice daily have been effective for some children.
Schedule of Beclomethasone Inhalers
Storage Requirements for Beclomethasone Inhalers
Store this medication at room temperature away from moisture and heat.
Effects of Missed Dosage of Beclomethasone Inhalers
Inhale the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Beclomethasone Inhalers
Give supportive measures and symptomatic treatment.

Home Delivery for Beclomethasone Inhalers in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including beclomethasone inhalers.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for beclomethasone inhalers and other medicines and health products. Home delivery services for beclomethasone inhalers may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take beclomethasone inhalers only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for beclomethasone inhalers before they complete the sale. You can get this information while placing the order for beclomethasone inhalers with the pharmacy.

Beclomethasone Inhalers is a generic medicine name and there are several brands available for it. Some of the brands for beclomethasone inhalers might be better known than beclomethasone inhalers itself. If the pharmacy that's willing to deliver medicines to your home doesn't have beclomethasone inhalers in stock, you can ask for one of the branded alternatives for beclomethasone inhalers.