General anaesthesia: It is often administered during the induction of anaesthesia to relax muscles of the jaw, neck and airway and thereby facilitate laryngoscopy and endotracheal intubation. Following induction, continued muscle relaxation is required for many procedures to aid surgical exposure and to provide additional insurance of immobility.
Distribution- Widely distributed into the extra cellular space. 82% bound to the plasma proteins
Metabolism- Metabolized in plasma by Hoffman degradation and ester hydrolysis
Excretion- Excreted through urine and feces
2. Inadequate or prolonged block.
3. Hypotension vasodilatation.
10. Reaction at the injection site.
3. Electrolyte imbalance.
4. Myasthenia gravis.
5. Long term infusion.
Enflurane, Isoflurane, Halothane, Aminoglycosides, Polypeptide antibiotics (bacitracin, capreomycin, colistimethate, polymyxin B) Clindamycin, Linomycin, Lithium, Verapamil, Trimethaphan, Procainamide & Quinidine: Enhance the neuromuscular blockade.
Magnesium Salts: Reversal of neuromuscular blockade unsatisfactory therefore dose of Atracurium besylate should be lowered.
Other muscular relaxants: May have both synergistic and antagonist effect.
Phenytoin & Theophylline: Resistance to or reversal of neuromuscular blockade of atracurium.
Succinylcholine: Enhances atracurium induced neuromuscular blockade.
For muscle relaxation in surgical anesthesia-
Induction - 0.3-0.6 mg/kg body wt. i.v
Maintenance - 0.1-0.2 mg body wt. /hour by continuous i.v. infusion.
Premature neonates: 0.3 mg/kg.
Home Delivery for Atracurium in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including atracurium.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for atracurium and other medicines and health products. Home delivery services for atracurium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take atracurium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for atracurium before they complete the sale. You can get this information while placing the order for atracurium with the pharmacy.
Atracurium is a generic medicine name and there are several brands available for it. Some of the brands for atracurium might be better known than atracurium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have atracurium in stock, you can ask for one of the branded alternatives for atracurium.